Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors

Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors

Astrocytes are now considered as key players in brain information processing because of their newly discovered roles in synapse formation and plasticity, energy metabolism and blood flow regulation. However, our understanding of astrocyte function is still fragmented compared to other brain cell typ...

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Bibliographic Details
Main Authors: Nicolas eMerienne, Juliette eLe Douce, Emilie eFaivre, Nicole eDéglon, Gilles eBonvento
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Astrocytes
Gene Therapy
Tropism
Lentiviral vectors
AAV vectors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00106/full

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