Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis
PurposeThe diagnosis of acute pyelonephritis (APN) is often difficult, as its clinical and biological manifestations are non-specific in children. If not treated quickly and adequately, however, APN may cause irreversible renal damage, possibly leading to hypertension and chronic renal failure. We w...
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| Format: | Article |
| Language: | English |
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Korean Pediatric Society
2011-05-01
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| Series: | Korean Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://kjp.or.kr/upload/pdf/kjped-54-212.pdf |
| _version_ | 1818943734838984704 |
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| author | Jeongmin Lee Duck Geun Kwon Se Jin Park Ki-Soo Pai |
| author_facet | Jeongmin Lee Duck Geun Kwon Se Jin Park Ki-Soo Pai |
| author_sort | Jeongmin Lee |
| collection | DOAJ |
| description | PurposeThe diagnosis of acute pyelonephritis (APN) is often difficult, as its clinical and biological manifestations are non-specific in children. If not treated quickly and adequately, however, APN may cause irreversible renal damage, possibly leading to hypertension and chronic renal failure. We were suspecting the diagnostic value of 99mTc-dimercaptosuccinic acid (DMSA) scan by experiences and so compared the results of DMSA scan to those of multi-detector row computed tomography (MDCT).MethodsWe retrospectively selected and analyzed 81 patients who were diagnosed as APN by MDCT during evaluation of their acute abdomen in emergency room and then received DMSA scan also for the diagnostic work-up of APN after admission. We evaluated the results of imaging studies and compared the diagnostic value of each method by age groups, <2 years (n=45) and ≥2 years (n=36).ResultsAmong total 81 patients with MDCT-proven APN. DMSA scan was diagnostic only in 55 children (68%), while the remaining 26 children (32%) showed false negative normal findings. These 26 patients were predominantly male with average age of 21 months and most of them, 19 (73.1%) were <2 years of age.ConclusionDMSA scan has obvious limitation compared to MDCT in depicting acute inflammatory lesions of kidney in children with APN, especially in early childhood less than 2 years of age. MDCT showed hidden lesions of APN, those were undetectable through DMSA scan in children. |
| first_indexed | 2024-12-20T07:32:02Z |
| format | Article |
| id | doaj.art-47bf5536fa5f432799b7d2068d568b51 |
| institution | Directory Open Access Journal |
| issn | 1738-1061 2092-7258 |
| language | English |
| last_indexed | 2024-12-20T07:32:02Z |
| publishDate | 2011-05-01 |
| publisher | Korean Pediatric Society |
| record_format | Article |
| series | Korean Journal of Pediatrics |
| spelling | doaj.art-47bf5536fa5f432799b7d2068d568b512022-12-21T19:48:23ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582011-05-0154521221810.3345/kjp.2011.54.5.2122011540506Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritisJeongmin Lee0Duck Geun Kwon1Se Jin Park2Ki-Soo Pai3Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.PurposeThe diagnosis of acute pyelonephritis (APN) is often difficult, as its clinical and biological manifestations are non-specific in children. If not treated quickly and adequately, however, APN may cause irreversible renal damage, possibly leading to hypertension and chronic renal failure. We were suspecting the diagnostic value of 99mTc-dimercaptosuccinic acid (DMSA) scan by experiences and so compared the results of DMSA scan to those of multi-detector row computed tomography (MDCT).MethodsWe retrospectively selected and analyzed 81 patients who were diagnosed as APN by MDCT during evaluation of their acute abdomen in emergency room and then received DMSA scan also for the diagnostic work-up of APN after admission. We evaluated the results of imaging studies and compared the diagnostic value of each method by age groups, <2 years (n=45) and ≥2 years (n=36).ResultsAmong total 81 patients with MDCT-proven APN. DMSA scan was diagnostic only in 55 children (68%), while the remaining 26 children (32%) showed false negative normal findings. These 26 patients were predominantly male with average age of 21 months and most of them, 19 (73.1%) were <2 years of age.ConclusionDMSA scan has obvious limitation compared to MDCT in depicting acute inflammatory lesions of kidney in children with APN, especially in early childhood less than 2 years of age. MDCT showed hidden lesions of APN, those were undetectable through DMSA scan in children.http://kjp.or.kr/upload/pdf/kjped-54-212.pdfAcute pyelonephritisMulti-detector row computed tomographyTc-dimercaptosuccinic acid scanChild |
| spellingShingle | Jeongmin Lee Duck Geun Kwon Se Jin Park Ki-Soo Pai Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis Korean Journal of Pediatrics Acute pyelonephritis Multi-detector row computed tomography Tc-dimercaptosuccinic acid scan Child |
| title | Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis |
| title_full | Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis |
| title_fullStr | Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis |
| title_full_unstemmed | Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis |
| title_short | Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis |
| title_sort | discordant findings on dimercaptosuccinic acid scintigraphy in children with multi detector row computed tomography proven acute pyelonephritis |
| topic | Acute pyelonephritis Multi-detector row computed tomography Tc-dimercaptosuccinic acid scan Child |
| url | http://kjp.or.kr/upload/pdf/kjped-54-212.pdf |
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