Aldosterone-induced endothelial dysfunction of rat aorta: role of poly(ADP-ribose) activation
Introduction. The aim of this study was to investigate whether activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) contributes to the development of aldosterone-induced endothelial dysfunction and treatment with the potent PARP inhibitor 1,5-isoquinolinediol (3 mg/kg/day, i.p.) could...
Main Authors: | Arda Tasatargil, Merih Tekcan, Ciler Celik-Ozenci, Nazli Ece Gungor, Bedriniam Dalkiran |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2009-09-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.1177/1470320309343655 |
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