Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -

Background Hypertrophic osteoarthropathy (HOA) is a rare clinical condition including an abnormal periosteal reaction in the long bones that causes painful swelling and tenderness of the extremities, digital clubbing, arthritis, synovitis, and joint effusions. Most cases are associated with tumorous...

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Main Authors: Kyung Seo Oh, Seung Young Lee, Se-Hee Min, Choongun Ryu, Hwa-Yong Shin
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2021-07-01
Series:Anesthesia and Pain Medicine
Subjects:
Online Access:http://www.anesth-pain-med.org/upload/pdf/apm-20092.pdf
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author Kyung Seo Oh
Seung Young Lee
Se-Hee Min
Choongun Ryu
Hwa-Yong Shin
author_facet Kyung Seo Oh
Seung Young Lee
Se-Hee Min
Choongun Ryu
Hwa-Yong Shin
author_sort Kyung Seo Oh
collection DOAJ
description Background Hypertrophic osteoarthropathy (HOA) is a rare clinical condition including an abnormal periosteal reaction in the long bones that causes painful swelling and tenderness of the extremities, digital clubbing, arthritis, synovitis, and joint effusions. Most cases are associated with tumorous conditions and most commonly with lung cancer. HOA has been rarely reported in association with other cancers. Case A patient with a history of recurrent renal cell carcinoma was referred to our clinic with bilateral leg pain, knee joint effusion, and arthritis. Simple radiography and bone scintigraphy confirmed a diagnosis of HOA. Oral non-steroidal anti-inflammatory drugs, joint fluid aspiration, and intra-articular injection of pain medications were found to be effective in the management of HOA pain. Conclusions HOA prognosis depends on the underlying disease, therefore, cancer treatment is critical. This case demonstrates the need to consider HOA in patients with various malignancies who present with bone or joint pain of the extremities.
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spelling doaj.art-47c08c0c13a343e39fc38e1a45740f372023-05-17T05:48:30ZengKorean Society of AnesthesiologistsAnesthesia and Pain Medicine1975-51712383-79772021-07-0116329029410.17085/apm.200921078Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -Kyung Seo Oh0Seung Young Lee1Se-Hee Min2Choongun Ryu3Hwa-Yong Shin4 Department of Anesthesiology and Pain Medicine, Chung-Ang University Hospital, Seoul, Korea Department of Anesthesiology and Pain Medicine, Chung-Ang University Hospital, Seoul, Korea Department of Anesthesiology and Pain Medicine, Chung-Ang University Hospital, Seoul, Korea Department of Anesthesiology and Pain Medicine, Chung-Ang University Hospital, Seoul, Korea Department of Anesthesiology and Pain Medicine, Chung-Ang University Hospital, Seoul, KoreaBackground Hypertrophic osteoarthropathy (HOA) is a rare clinical condition including an abnormal periosteal reaction in the long bones that causes painful swelling and tenderness of the extremities, digital clubbing, arthritis, synovitis, and joint effusions. Most cases are associated with tumorous conditions and most commonly with lung cancer. HOA has been rarely reported in association with other cancers. Case A patient with a history of recurrent renal cell carcinoma was referred to our clinic with bilateral leg pain, knee joint effusion, and arthritis. Simple radiography and bone scintigraphy confirmed a diagnosis of HOA. Oral non-steroidal anti-inflammatory drugs, joint fluid aspiration, and intra-articular injection of pain medications were found to be effective in the management of HOA pain. Conclusions HOA prognosis depends on the underlying disease, therefore, cancer treatment is critical. This case demonstrates the need to consider HOA in patients with various malignancies who present with bone or joint pain of the extremities.http://www.anesth-pain-med.org/upload/pdf/apm-20092.pdfparaneoplastic syndromeperiostitisrenal cell carcinomascintigraphysecondary hypertrophic osteoarthropathy
spellingShingle Kyung Seo Oh
Seung Young Lee
Se-Hee Min
Choongun Ryu
Hwa-Yong Shin
Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -
Anesthesia and Pain Medicine
paraneoplastic syndrome
periostitis
renal cell carcinoma
scintigraphy
secondary hypertrophic osteoarthropathy
title Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -
title_full Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -
title_fullStr Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -
title_full_unstemmed Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -
title_short Hypertrophic osteoarthropathy in renal cell carcinoma - A case report -
title_sort hypertrophic osteoarthropathy in renal cell carcinoma a case report
topic paraneoplastic syndrome
periostitis
renal cell carcinoma
scintigraphy
secondary hypertrophic osteoarthropathy
url http://www.anesth-pain-med.org/upload/pdf/apm-20092.pdf
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AT seungyounglee hypertrophicosteoarthropathyinrenalcellcarcinomaacasereport
AT seheemin hypertrophicosteoarthropathyinrenalcellcarcinomaacasereport
AT choongunryu hypertrophicosteoarthropathyinrenalcellcarcinomaacasereport
AT hwayongshin hypertrophicosteoarthropathyinrenalcellcarcinomaacasereport