In Silico Identification of Lead Compounds for Pseudomonas Aeruginosa PqsA Enzyme: Computational Study to Block Biofilm Formation

In Silico Identification of Lead Compounds for Pseudomonas Aeruginosa PqsA Enzyme: Computational Study to Block Biofilm Formation

<i>Pseudomonas aeruginosa</i> is an opportunistic Gram-negative bacterium implicated in acute and chronic nosocomial infections and a leading cause of patient mortality. <i>Pseudomonas aeruginosa</i> infections are frequently associated with the development of biofilms, which...

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Bibliographic Details
Main Authors: Muhammad Shahab, Muhammad Danial, Taimur Khan, Chaoqun Liang, Xiuyuan Duan, Daixi Wang, Hanzi Gao, Guojun Zheng
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
pqsA gene
pharmacophore-based virtual screening
ZINC
Cambridge
MD simulation
biofilms
Online Access:https://www.mdpi.com/2227-9059/11/3/961

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https://www.mdpi.com/2227-9059/11/3/961

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