Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort Study
Milk and fermented milk consumption has been linked to health and mortality but the association with Parkinson’s disease (PD) is uncertain. We conducted a study to investigate whether milk and fermented milk intakes are associated with incident PD. This cohort study included 81,915 Swedish adults (w...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/9/2763 |
| _version_ | 1797554054120865792 |
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| author | Erika Olsson Liisa Byberg Jonas Höijer Lena Kilander Susanna C. Larsson |
| author_facet | Erika Olsson Liisa Byberg Jonas Höijer Lena Kilander Susanna C. Larsson |
| author_sort | Erika Olsson |
| collection | DOAJ |
| description | Milk and fermented milk consumption has been linked to health and mortality but the association with Parkinson’s disease (PD) is uncertain. We conducted a study to investigate whether milk and fermented milk intakes are associated with incident PD. This cohort study included 81,915 Swedish adults (with a mean age of 62 years) who completed a questionnaire, including questions about milk and fermented milk (soured milk and yogurt) intake, in 1997. PD cases were identified through linkage with the Swedish National Patient and Cause of Death Registers. Multivariable-adjusted hazard ratios were obtained from Cox proportional hazards regression models. During a mean follow-up of 14.9 years, 1251 PD cases were identified in the cohort. Compared with no or low milk consumption (<40 mL/day), the hazard ratios of PD across quintiles of milk intake were 1.29 (95% CI 1.07, 1.56) for 40–159 mL/day, 1.19 (95% CI 0.99, 1.42) for 160–200 mL/day, 1.29 (95% CI 1.08, 1.53) for 201–400 mL/day, and 1.14 (95% CI 0.93, 1.40) for >400 mL/day. Fermented milk intake was not associated with PD. We found a weak association between milk intake and increased risk of PD but no dose–response relationship. Fermented milk intake was not associated with increased risk of PD. |
| first_indexed | 2024-03-10T16:25:21Z |
| format | Article |
| id | doaj.art-47c60aca25cf4f089f2fd3725edbd216 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T16:25:21Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-47c60aca25cf4f089f2fd3725edbd2162023-11-20T13:15:35ZengMDPI AGNutrients2072-66432020-09-01129276310.3390/nu12092763Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort StudyErika Olsson0Liisa Byberg1Jonas Höijer2Lena Kilander3Susanna C. Larsson4Department of Surgical Sciences, Uppsala University, SE-751 85 Uppsala, SwedenDepartment of Surgical Sciences, Uppsala University, SE-751 85 Uppsala, SwedenDepartment of Surgical Sciences, Uppsala University, SE-751 85 Uppsala, SwedenPublic Health and Caring Sciences, Geriatrics, Uppsala University, SE-751 22 Uppsala, SwedenDepartment of Surgical Sciences, Uppsala University, SE-751 85 Uppsala, SwedenMilk and fermented milk consumption has been linked to health and mortality but the association with Parkinson’s disease (PD) is uncertain. We conducted a study to investigate whether milk and fermented milk intakes are associated with incident PD. This cohort study included 81,915 Swedish adults (with a mean age of 62 years) who completed a questionnaire, including questions about milk and fermented milk (soured milk and yogurt) intake, in 1997. PD cases were identified through linkage with the Swedish National Patient and Cause of Death Registers. Multivariable-adjusted hazard ratios were obtained from Cox proportional hazards regression models. During a mean follow-up of 14.9 years, 1251 PD cases were identified in the cohort. Compared with no or low milk consumption (<40 mL/day), the hazard ratios of PD across quintiles of milk intake were 1.29 (95% CI 1.07, 1.56) for 40–159 mL/day, 1.19 (95% CI 0.99, 1.42) for 160–200 mL/day, 1.29 (95% CI 1.08, 1.53) for 201–400 mL/day, and 1.14 (95% CI 0.93, 1.40) for >400 mL/day. Fermented milk intake was not associated with PD. We found a weak association between milk intake and increased risk of PD but no dose–response relationship. Fermented milk intake was not associated with increased risk of PD.https://www.mdpi.com/2072-6643/12/9/2763milkParkinson’s diseaserisk factors |
| spellingShingle | Erika Olsson Liisa Byberg Jonas Höijer Lena Kilander Susanna C. Larsson Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort Study Nutrients milk Parkinson’s disease risk factors |
| title | Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort Study |
| title_full | Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort Study |
| title_fullStr | Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort Study |
| title_full_unstemmed | Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort Study |
| title_short | Milk and Fermented Milk Intake and Parkinson’s Disease: Cohort Study |
| title_sort | milk and fermented milk intake and parkinson s disease cohort study |
| topic | milk Parkinson’s disease risk factors |
| url | https://www.mdpi.com/2072-6643/12/9/2763 |
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