One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
A simple and clean one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile derivatives using 6-amino uracil, various aromatic aldehydes and malononitrile in the presence of sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) is described....
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Format: | Article |
Language: | English |
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Elsevier
2015-11-01
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Series: | Journal of Saudi Chemical Society |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S131961031400091X |
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author | Ghodsi Mohammadi Ziarani Narges Hosseini Nasab Mahshid Rahimifard Ali Abolhasani Soorki |
author_facet | Ghodsi Mohammadi Ziarani Narges Hosseini Nasab Mahshid Rahimifard Ali Abolhasani Soorki |
author_sort | Ghodsi Mohammadi Ziarani |
collection | DOAJ |
description | A simple and clean one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile derivatives using 6-amino uracil, various aromatic aldehydes and malononitrile in the presence of sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) is described. Some of synthesized pyrido[2,3-d]pyrimidines showed antimicrobial activities against some fungi and gram positive and negative bacteria. |
first_indexed | 2024-04-12T12:44:55Z |
format | Article |
id | doaj.art-47c74bd6a18f498c8122c5b1d45195b2 |
institution | Directory Open Access Journal |
issn | 1319-6103 |
language | English |
last_indexed | 2024-04-12T12:44:55Z |
publishDate | 2015-11-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Saudi Chemical Society |
spelling | doaj.art-47c74bd6a18f498c8122c5b1d45195b22022-12-22T03:32:39ZengElsevierJournal of Saudi Chemical Society1319-61032015-11-0119667668110.1016/j.jscs.2014.06.007One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activitiesGhodsi Mohammadi Ziarani0Narges Hosseini Nasab1Mahshid Rahimifard2Ali Abolhasani Soorki3Department of Chemistry, Alzahra University, Vanak Square, PO Box No. 19938939973, Tehran, IranDepartment of Chemistry, Alzahra University, Vanak Square, PO Box No. 19938939973, Tehran, IranDepartment of Chemistry, Alzahra University, Vanak Square, PO Box No. 19938939973, Tehran, IranShahid Beheshti University, Research Institute of Applied Sciences, Academic Center of Education, Culture & Research, Tehran, IranA simple and clean one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile derivatives using 6-amino uracil, various aromatic aldehydes and malononitrile in the presence of sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) is described. Some of synthesized pyrido[2,3-d]pyrimidines showed antimicrobial activities against some fungi and gram positive and negative bacteria.http://www.sciencedirect.com/science/article/pii/S131961031400091X6-Amino uracilAldehydesMalononitrileFunctionalized SBA-15Multicomponent reactionSolvent free |
spellingShingle | Ghodsi Mohammadi Ziarani Narges Hosseini Nasab Mahshid Rahimifard Ali Abolhasani Soorki One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities Journal of Saudi Chemical Society 6-Amino uracil Aldehydes Malononitrile Functionalized SBA-15 Multicomponent reaction Solvent free |
title | One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities |
title_full | One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities |
title_fullStr | One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities |
title_full_unstemmed | One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities |
title_short | One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities |
title_sort | one pot synthesis of pyrido 2 3 d pyrimidine derivatives using sulfonic acid functionalized sba 15 and the study on their antimicrobial activities |
topic | 6-Amino uracil Aldehydes Malononitrile Functionalized SBA-15 Multicomponent reaction Solvent free |
url | http://www.sciencedirect.com/science/article/pii/S131961031400091X |
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