One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities

A simple and clean one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile derivatives using 6-amino uracil, various aromatic aldehydes and malononitrile in the presence of sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) is described....

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Main Authors: Ghodsi Mohammadi Ziarani, Narges Hosseini Nasab, Mahshid Rahimifard, Ali Abolhasani Soorki
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S131961031400091X
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author Ghodsi Mohammadi Ziarani
Narges Hosseini Nasab
Mahshid Rahimifard
Ali Abolhasani Soorki
author_facet Ghodsi Mohammadi Ziarani
Narges Hosseini Nasab
Mahshid Rahimifard
Ali Abolhasani Soorki
author_sort Ghodsi Mohammadi Ziarani
collection DOAJ
description A simple and clean one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile derivatives using 6-amino uracil, various aromatic aldehydes and malononitrile in the presence of sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) is described. Some of synthesized pyrido[2,3-d]pyrimidines showed antimicrobial activities against some fungi and gram positive and negative bacteria.
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spelling doaj.art-47c74bd6a18f498c8122c5b1d45195b22022-12-22T03:32:39ZengElsevierJournal of Saudi Chemical Society1319-61032015-11-0119667668110.1016/j.jscs.2014.06.007One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activitiesGhodsi Mohammadi Ziarani0Narges Hosseini Nasab1Mahshid Rahimifard2Ali Abolhasani Soorki3Department of Chemistry, Alzahra University, Vanak Square, PO Box No. 19938939973, Tehran, IranDepartment of Chemistry, Alzahra University, Vanak Square, PO Box No. 19938939973, Tehran, IranDepartment of Chemistry, Alzahra University, Vanak Square, PO Box No. 19938939973, Tehran, IranShahid Beheshti University, Research Institute of Applied Sciences, Academic Center of Education, Culture & Research, Tehran, IranA simple and clean one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile derivatives using 6-amino uracil, various aromatic aldehydes and malononitrile in the presence of sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) is described. Some of synthesized pyrido[2,3-d]pyrimidines showed antimicrobial activities against some fungi and gram positive and negative bacteria.http://www.sciencedirect.com/science/article/pii/S131961031400091X6-Amino uracilAldehydesMalononitrileFunctionalized SBA-15Multicomponent reactionSolvent free
spellingShingle Ghodsi Mohammadi Ziarani
Narges Hosseini Nasab
Mahshid Rahimifard
Ali Abolhasani Soorki
One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
Journal of Saudi Chemical Society
6-Amino uracil
Aldehydes
Malononitrile
Functionalized SBA-15
Multicomponent reaction
Solvent free
title One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
title_full One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
title_fullStr One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
title_full_unstemmed One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
title_short One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
title_sort one pot synthesis of pyrido 2 3 d pyrimidine derivatives using sulfonic acid functionalized sba 15 and the study on their antimicrobial activities
topic 6-Amino uracil
Aldehydes
Malononitrile
Functionalized SBA-15
Multicomponent reaction
Solvent free
url http://www.sciencedirect.com/science/article/pii/S131961031400091X
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