Revealing the Sequence Characteristics and Molecular Mechanisms of ACE Inhibitory Peptides by Comprehensive Characterization of 160,000 Tetrapeptides

Revealing the Sequence Characteristics and Molecular Mechanisms of ACE Inhibitory Peptides by Comprehensive Characterization of 160,000 Tetrapeptides

Chronic diseases, such as hypertension, cause great harm to human health. Conventional drugs have promising therapeutic effects, but also cause significant side effects. Food-sourced angiotensin-converting enzyme (ACE) inhibitory peptides are an excellent therapeutic alternative to pharmaceuticals,...

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Bibliographic Details
Main Authors: Mingzhe Ma, Yinghui Feng, Yulu Miao, Qiang Shen, Shuting Tang, Juan Dong, John Z. H. Zhang, Lujia Zhang
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Foods
Subjects:
angiotensin-converting enzyme (ACE)
ACE inhibitory peptides
tetrapeptides
molecular docking
molecular dynamics simulations
Online Access:https://www.mdpi.com/2304-8158/12/8/1573

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