Association between C-reactive protein levels and physical fitness in 7 to 9 year old children at poor elementary schools in Surakarta, Indonesia
Background Data regarding inflammatory factors in children are not so well developed as in adults. Higher levels of physical fitness may be helpful in modifying the low-grade inflammatory state that is indexed by C-reactive protein (CRP) levels. Objective To evaluate the association ...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Indonesian Pediatric Society Publishing House
2009-04-01
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| Series: | Paediatrica Indonesiana |
| Subjects: | |
| Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/460 |
| Summary: | Background Data regarding inflammatory factors in children are
not so well developed as in adults. Higher levels of physical fitness
may be helpful in modifying the low-grade inflammatory state that
is indexed by C-reactive protein (CRP) levels.
Objective To evaluate the association of physical fitness with CRP
levels in children and to identify the possible related factors.
Methods This cross-sectional study was conducted at poor
elementary schools in Surakarta, Indonesia using a group of 217
underweight children aged from 7 to 9 years old. Physical fitness
was assessed using a modified Harvard Step Test. CRP levels were
measured using a high-sensitivity assay. The association between
physical fitness and CRP level was assessed using linear regression
analysis. Multivariate analyses were used to adjust covariates,
and statistical analyses were performed using SPSS for Windows
software version 15.0.
Results Subjects were 48% female and 52% male, and eleven
children (5%) had a CRP level > 5 mg/L. Mean fitness level and
CRP level did not differ by age and gender. Fitness level was not
inversely correlated with CRP (r=0.10, P=0.14). Physical fitness
was significantly correlated with BMI (r=0.14; P=0.04), physical
activity [0R=3.3 (95% CI 1.7 to 6.4)], and fat intake [0R=0.5
(95% CI 0.2 to 0.9) ].
Conclusion These findings indicate that physical fitness is not
inversely correlated to CRP levels in children. However, our
study reveased an association between high fat intake and low
physical fitness as well as a significant association between
high physical activiry and physical fitness. |
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| ISSN: | 0030-9311 2338-476X |