An Improved In Vitro Blood-Brain Barrier Model for the Evaluation of Drug Permeability Using Transwell with Shear Stress

An Improved In Vitro Blood-Brain Barrier Model for the Evaluation of Drug Permeability Using Transwell with Shear Stress

The development of drugs targeting the central nervous system (CNS) is challenging because of the presence of the Blood-Brain barrier (BBB). Developing physiologically relevant in vitro BBB models for evaluating drug permeability and predicting the activity of drug candidates is crucial. The transwe...

Full description

Bibliographic Details
Main Authors: Junhyeong Kim, Seong-Ah Shin, Chang Sup Lee, Hye Jin Chung
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
blood-brain barrier
permeability
transwell
in vitro BBB model
shear stress
annular shaking dish
Online Access:https://www.mdpi.com/1999-4923/16/1/48

Similar Items

Similar Items