ARHGAP15 promotes metastatic colonization in gastric cancer by suppressing RAC1-ROS pathway.

ARHGAP15 promotes metastatic colonization in gastric cancer by suppressing RAC1-ROS pathway.

The molecular mechanism of tumor metastasis, especially how metastatic tumor cells colonize in a distant site, remains poorly understood. Here we reported that ARHGAP15, a Rho GTPase activating protein, enhanced gastric cancer (GC) metastatic colonization, which was quite different from its reported...

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Bibliographic Details
Main Authors: Fei-Fei Zhang, Chen Jiang, Dong-Ping Jiang, Yu-Zhu Cui, Xin-Yue Wang, Liang-Zhan Sun, Miao Chen, Ka-On Lam, Sha-Yi Wu, Krista Verhoeft, Dora Lai-Wan Kwong, Xin-Yuan Guan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010640

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