Exploring the Risk Factors and Possible Role of Calcium in Infective Endocarditis
Infective endocarditis (IE) is a severe and potentially life-threatening infection that affects the endocardium, the inner lining of the heart chambers and valves. Although rare, it is a potentially fatal condition, with an incidence of 3–10 cases per 100,000 people per year in developed countries a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/14/2386 |
| _version_ | 1797589653833908224 |
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| author | Yen-Shou Kuo Yuan-Ming Tsai |
| author_facet | Yen-Shou Kuo Yuan-Ming Tsai |
| author_sort | Yen-Shou Kuo |
| collection | DOAJ |
| description | Infective endocarditis (IE) is a severe and potentially life-threatening infection that affects the endocardium, the inner lining of the heart chambers and valves. Although rare, it is a potentially fatal condition, with an incidence of 3–10 cases per 100,000 people per year in developed countries and a mortality rate of up to 30% within 30 days. Early identification and diagnosis are critical for improving outcomes. The diagnosis of IE typically involves a combination of biomarkers, blood cultures, and echocardiography. However, currently, there are no specific biomarkers for the early detection of IE. Given the lack of specific biomarkers for IE, serum calcium levels have been suggested to play a unique role in IE. There have been few articles on the correlation between serum calcium and IE, suggesting that patients with endocarditis and lower levels of serum calcium may have a poorer prognosis. Therefore, in this article, we focus on biomarkers of endocarditis and discuss the evidence showing serum calcium as a potential indicator of IE. |
| first_indexed | 2024-03-11T01:09:36Z |
| format | Article |
| id | doaj.art-47db4e9ea009466e990933230554c025 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T01:09:36Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-47db4e9ea009466e990933230554c0252023-11-18T18:58:04ZengMDPI AGDiagnostics2075-44182023-07-011314238610.3390/diagnostics13142386Exploring the Risk Factors and Possible Role of Calcium in Infective EndocarditisYen-Shou Kuo0Yuan-Ming Tsai1Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei City 11490, TaiwanDivision of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei City 11490, TaiwanInfective endocarditis (IE) is a severe and potentially life-threatening infection that affects the endocardium, the inner lining of the heart chambers and valves. Although rare, it is a potentially fatal condition, with an incidence of 3–10 cases per 100,000 people per year in developed countries and a mortality rate of up to 30% within 30 days. Early identification and diagnosis are critical for improving outcomes. The diagnosis of IE typically involves a combination of biomarkers, blood cultures, and echocardiography. However, currently, there are no specific biomarkers for the early detection of IE. Given the lack of specific biomarkers for IE, serum calcium levels have been suggested to play a unique role in IE. There have been few articles on the correlation between serum calcium and IE, suggesting that patients with endocarditis and lower levels of serum calcium may have a poorer prognosis. Therefore, in this article, we focus on biomarkers of endocarditis and discuss the evidence showing serum calcium as a potential indicator of IE.https://www.mdpi.com/2075-4418/13/14/2386risk factorsendocarditisbiomarkersserum calcium |
| spellingShingle | Yen-Shou Kuo Yuan-Ming Tsai Exploring the Risk Factors and Possible Role of Calcium in Infective Endocarditis Diagnostics risk factors endocarditis biomarkers serum calcium |
| title | Exploring the Risk Factors and Possible Role of Calcium in Infective Endocarditis |
| title_full | Exploring the Risk Factors and Possible Role of Calcium in Infective Endocarditis |
| title_fullStr | Exploring the Risk Factors and Possible Role of Calcium in Infective Endocarditis |
| title_full_unstemmed | Exploring the Risk Factors and Possible Role of Calcium in Infective Endocarditis |
| title_short | Exploring the Risk Factors and Possible Role of Calcium in Infective Endocarditis |
| title_sort | exploring the risk factors and possible role of calcium in infective endocarditis |
| topic | risk factors endocarditis biomarkers serum calcium |
| url | https://www.mdpi.com/2075-4418/13/14/2386 |
| work_keys_str_mv | AT yenshoukuo exploringtheriskfactorsandpossibleroleofcalciumininfectiveendocarditis AT yuanmingtsai exploringtheriskfactorsandpossibleroleofcalciumininfectiveendocarditis |