Long-term health impacts of COVID-19 among 242,712 adults in England

Abstract The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested positive for SARS-CoV-2 infection and those who have re...

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Main Authors: Christina J. Atchison, Bethan Davies, Emily Cooper, Adam Lound, Matthew Whitaker, Adam Hampshire, Adriana Azor, Christl A. Donnelly, Marc Chadeau-Hyam, Graham S. Cooke, Helen Ward, Paul Elliott
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41879-2
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author Christina J. Atchison
Bethan Davies
Emily Cooper
Adam Lound
Matthew Whitaker
Adam Hampshire
Adriana Azor
Christl A. Donnelly
Marc Chadeau-Hyam
Graham S. Cooke
Helen Ward
Paul Elliott
author_facet Christina J. Atchison
Bethan Davies
Emily Cooper
Adam Lound
Matthew Whitaker
Adam Hampshire
Adriana Azor
Christl A. Donnelly
Marc Chadeau-Hyam
Graham S. Cooke
Helen Ward
Paul Elliott
author_sort Christina J. Atchison
collection DOAJ
description Abstract The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested positive for SARS-CoV-2 infection and those who have recovered from COVID-19. Overall, 276,840/800,000 (34·6%) of invited participants took part. Mental health and health-related quality of life were worse among participants with ongoing persistent symptoms post-COVID compared with those who had never had COVID-19 or had recovered. In this study, median duration of COVID-related symptoms (N = 130,251) was 1·3 weeks (inter-quartile range 6 days to 2 weeks), with 7·5% and 5·2% reporting ongoing symptoms ≥12 weeks and ≥52 weeks respectively. Female sex, ≥1 comorbidity and being infected when Wild-type variant was dominant were associated with higher probability of symptoms lasting ≥12 weeks and longer recovery time in those with persistent symptoms. Although COVID-19 is usually of short duration, some adults experience persistent and burdensome illness.
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spelling doaj.art-47dd447bfacb4350a0f1ef3faffd497a2023-11-20T10:17:00ZengNature PortfolioNature Communications2041-17232023-10-0114111010.1038/s41467-023-41879-2Long-term health impacts of COVID-19 among 242,712 adults in EnglandChristina J. Atchison0Bethan Davies1Emily Cooper2Adam Lound3Matthew Whitaker4Adam Hampshire5Adriana Azor6Christl A. Donnelly7Marc Chadeau-Hyam8Graham S. Cooke9Helen Ward10Paul Elliott11School of Public Health, Imperial College LondonSchool of Public Health, Imperial College LondonSchool of Public Health, Imperial College LondonSchool of Public Health, Imperial College LondonSchool of Public Health, Imperial College LondonDepartment of Brain Sciences, Imperial College LondonDepartment of Brain Sciences, Imperial College LondonSchool of Public Health, Imperial College LondonSchool of Public Health, Imperial College LondonImperial College Healthcare NHS TrustSchool of Public Health, Imperial College LondonSchool of Public Health, Imperial College LondonAbstract The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested positive for SARS-CoV-2 infection and those who have recovered from COVID-19. Overall, 276,840/800,000 (34·6%) of invited participants took part. Mental health and health-related quality of life were worse among participants with ongoing persistent symptoms post-COVID compared with those who had never had COVID-19 or had recovered. In this study, median duration of COVID-related symptoms (N = 130,251) was 1·3 weeks (inter-quartile range 6 days to 2 weeks), with 7·5% and 5·2% reporting ongoing symptoms ≥12 weeks and ≥52 weeks respectively. Female sex, ≥1 comorbidity and being infected when Wild-type variant was dominant were associated with higher probability of symptoms lasting ≥12 weeks and longer recovery time in those with persistent symptoms. Although COVID-19 is usually of short duration, some adults experience persistent and burdensome illness.https://doi.org/10.1038/s41467-023-41879-2
spellingShingle Christina J. Atchison
Bethan Davies
Emily Cooper
Adam Lound
Matthew Whitaker
Adam Hampshire
Adriana Azor
Christl A. Donnelly
Marc Chadeau-Hyam
Graham S. Cooke
Helen Ward
Paul Elliott
Long-term health impacts of COVID-19 among 242,712 adults in England
Nature Communications
title Long-term health impacts of COVID-19 among 242,712 adults in England
title_full Long-term health impacts of COVID-19 among 242,712 adults in England
title_fullStr Long-term health impacts of COVID-19 among 242,712 adults in England
title_full_unstemmed Long-term health impacts of COVID-19 among 242,712 adults in England
title_short Long-term health impacts of COVID-19 among 242,712 adults in England
title_sort long term health impacts of covid 19 among 242 712 adults in england
url https://doi.org/10.1038/s41467-023-41879-2
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