Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumonia
Abstract Background Comparison of clinical findings, chest radiographs (CXR), lung ultrasound (LUS) findings, and C‐reactive protein (CRP) concentrations at admission and serial follow‐up in dogs with aspiration pneumonia (AP) is lacking. Hypothesis Lung ultrasound lesions in dogs with AP are simila...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-03-01
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| Series: | Journal of Veterinary Internal Medicine |
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| Online Access: | https://doi.org/10.1111/jvim.16379 |
| _version_ | 1828857300848214016 |
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| author | Nina Fernandes Rodrigues Léna Giraud Géraldine Bolen Aline Fastrès Cécile Clercx Søren Boysen Frédéric Billen Kris Gommeren |
| author_facet | Nina Fernandes Rodrigues Léna Giraud Géraldine Bolen Aline Fastrès Cécile Clercx Søren Boysen Frédéric Billen Kris Gommeren |
| author_sort | Nina Fernandes Rodrigues |
| collection | DOAJ |
| description | Abstract Background Comparison of clinical findings, chest radiographs (CXR), lung ultrasound (LUS) findings, and C‐reactive protein (CRP) concentrations at admission and serial follow‐up in dogs with aspiration pneumonia (AP) is lacking. Hypothesis Lung ultrasound lesions in dogs with AP are similar to those described in humans with community‐acquired pneumonia (comAP); the severity of CXR and LUS lesions are similar; normalization of CRP concentration precedes resolution of imaging abnormalities and more closely reflects the clinical improvement of dogs. Animals Seventeen dogs with AP. Methods Prospective observational study. Clinical examination, CXR, LUS, and CRP measurements performed at admission (n = 17), 2 weeks (n = 13), and 1 month after diagnosis (n = 6). All dogs received antimicrobial therapy. Lung ultrasound and CXR canine aspiration scoring systems used to compare abnormalities. Results B‐lines and shred signs with or without bronchograms were identified on LUS in 14 of 17 and 16 of 17, at admission. Chest radiographs and LUS scores differed significantly using both canine AP scoring systems at each time point (18 regions per dog, P < .001). Clinical and CRP normalization occurred in all dogs during follow up. Shred signs disappeared on LUS in all but 1 of 6 dogs at 1 month follow‐up, while B‐lines and CXR abnormalities persisted in 4 of 6 and all dogs, respectively. Conclusion and Clinical Importance Lung ultrasound findings resemble those of humans with comAP and differ from CXR findings. Shred signs and high CRP concentrations better reflect clinical findings during serial evaluation of dogs. |
| first_indexed | 2024-12-13T01:32:43Z |
| format | Article |
| id | doaj.art-47ddb7c52d7b425d9c69fb01ef3b74d0 |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-12-13T01:32:43Z |
| publishDate | 2022-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-47ddb7c52d7b425d9c69fb01ef3b74d02022-12-22T00:03:57ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762022-03-0136274375210.1111/jvim.16379Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumoniaNina Fernandes Rodrigues0Léna Giraud1Géraldine Bolen2Aline Fastrès3Cécile Clercx4Søren Boysen5Frédéric Billen6Kris Gommeren7Department of Clinical Sciences University of Liège, Faculty of Veterinary Medicine Liège BelgiumDepartment of Clinical Sciences University of Liège, Faculty of Veterinary Medicine Liège BelgiumDepartment of Clinical Sciences University of Liège, Faculty of Veterinary Medicine Liège BelgiumDepartment of Clinical Sciences University of Liège, Faculty of Veterinary Medicine Liège BelgiumDepartment of Clinical Sciences University of Liège, Faculty of Veterinary Medicine Liège BelgiumDepartment of Veterinary Clinical and Diagnostic Sciences University of Calgary Calgary CanadaDepartment of Clinical Sciences University of Liège, Faculty of Veterinary Medicine Liège BelgiumDepartment of Clinical Sciences University of Liège, Faculty of Veterinary Medicine Liège BelgiumAbstract Background Comparison of clinical findings, chest radiographs (CXR), lung ultrasound (LUS) findings, and C‐reactive protein (CRP) concentrations at admission and serial follow‐up in dogs with aspiration pneumonia (AP) is lacking. Hypothesis Lung ultrasound lesions in dogs with AP are similar to those described in humans with community‐acquired pneumonia (comAP); the severity of CXR and LUS lesions are similar; normalization of CRP concentration precedes resolution of imaging abnormalities and more closely reflects the clinical improvement of dogs. Animals Seventeen dogs with AP. Methods Prospective observational study. Clinical examination, CXR, LUS, and CRP measurements performed at admission (n = 17), 2 weeks (n = 13), and 1 month after diagnosis (n = 6). All dogs received antimicrobial therapy. Lung ultrasound and CXR canine aspiration scoring systems used to compare abnormalities. Results B‐lines and shred signs with or without bronchograms were identified on LUS in 14 of 17 and 16 of 17, at admission. Chest radiographs and LUS scores differed significantly using both canine AP scoring systems at each time point (18 regions per dog, P < .001). Clinical and CRP normalization occurred in all dogs during follow up. Shred signs disappeared on LUS in all but 1 of 6 dogs at 1 month follow‐up, while B‐lines and CXR abnormalities persisted in 4 of 6 and all dogs, respectively. Conclusion and Clinical Importance Lung ultrasound findings resemble those of humans with comAP and differ from CXR findings. Shred signs and high CRP concentrations better reflect clinical findings during serial evaluation of dogs.https://doi.org/10.1111/jvim.16379acute phase proteinscanine aspiration pneumonia scorecommunity‐acquired pneumoniapoint of care ultrasoundsimplified canine aspiration pneumonia score |
| spellingShingle | Nina Fernandes Rodrigues Léna Giraud Géraldine Bolen Aline Fastrès Cécile Clercx Søren Boysen Frédéric Billen Kris Gommeren Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumonia Journal of Veterinary Internal Medicine acute phase proteins canine aspiration pneumonia score community‐acquired pneumonia point of care ultrasound simplified canine aspiration pneumonia score |
| title | Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumonia |
| title_full | Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumonia |
| title_fullStr | Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumonia |
| title_full_unstemmed | Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumonia |
| title_short | Comparison of lung ultrasound, chest radiographs, C‐reactive protein, and clinical findings in dogs treated for aspiration pneumonia |
| title_sort | comparison of lung ultrasound chest radiographs c reactive protein and clinical findings in dogs treated for aspiration pneumonia |
| topic | acute phase proteins canine aspiration pneumonia score community‐acquired pneumonia point of care ultrasound simplified canine aspiration pneumonia score |
| url | https://doi.org/10.1111/jvim.16379 |
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