In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives
A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polyc...
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MDPI AG
2018-04-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/23/4/979 |
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| author | Qiu-Chi Zhang Wen-Wei Zhang Liang Shen Zhi-Liang Shen Teck-Peng Loh |
| author_facet | Qiu-Chi Zhang Wen-Wei Zhang Liang Shen Zhi-Liang Shen Teck-Peng Loh |
| author_sort | Qiu-Chi Zhang |
| collection | DOAJ |
| description | A combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polycyclic structures in minimal steps remains a subject of great interest in both academia and industry. Herein we report an efficient method to assemble aryldihydronaphthalene derivatives via a cascade reaction of diarylalkynes with acrylates under the catalysis of a combined Lewis acid derived from In(III) salt and TMSBr. |
| first_indexed | 2024-12-13T04:29:34Z |
| format | Article |
| id | doaj.art-47df67d074b246dcb26ce58093ea5ed5 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T04:29:34Z |
| publishDate | 2018-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-47df67d074b246dcb26ce58093ea5ed52022-12-21T23:59:35ZengMDPI AGMolecules1420-30492018-04-0123497910.3390/molecules23040979molecules23040979In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene DerivativesQiu-Chi Zhang0Wen-Wei Zhang1Liang Shen2Zhi-Liang Shen3Teck-Peng Loh4Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, SingaporeBGI, BGI-Shenzhen, Shenzhen 518083, ChinaDivision of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, SingaporeInstitute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University, Nanjing 210009, ChinaDivision of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, SingaporeA combined Lewis acid system comprising of two or more Lewis acids occasionally exhibits augmented catalytic activity in organic transformations which are otherwise unrealizable by either of the components exclusively. On the other hand, the efficient construction of multiple new C-C bonds and polycyclic structures in minimal steps remains a subject of great interest in both academia and industry. Herein we report an efficient method to assemble aryldihydronaphthalene derivatives via a cascade reaction of diarylalkynes with acrylates under the catalysis of a combined Lewis acid derived from In(III) salt and TMSBr.http://www.mdpi.com/1420-3049/23/4/979indiumcombined Lewis acidcatalysiscascade reactionaryldihydronaphthalene |
| spellingShingle | Qiu-Chi Zhang Wen-Wei Zhang Liang Shen Zhi-Liang Shen Teck-Peng Loh In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives Molecules indium combined Lewis acid catalysis cascade reaction aryldihydronaphthalene |
| title | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_full | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_fullStr | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_full_unstemmed | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_short | In(III)-TMSBr-Catalyzed Cascade Reaction of Diarylalkynes with Acrylates for the Synthesis of Aryldihydronaphthalene Derivatives |
| title_sort | in iii tmsbr catalyzed cascade reaction of diarylalkynes with acrylates for the synthesis of aryldihydronaphthalene derivatives |
| topic | indium combined Lewis acid catalysis cascade reaction aryldihydronaphthalene |
| url | http://www.mdpi.com/1420-3049/23/4/979 |
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