Post-transplantation diabetes mellitus: an overview

This review presents an analysis of clinical and experimental studies related to post-transplantation diabetes mellitus (PTDM) ? a specific complication after solid organ transplantation. A search of the databases eLibrary, PubMed and Scopus using the keywords ?posttransplantation diabetes mellitus?...

Full description

Bibliographic Details
Main Authors: Igor Alexandrovich Sklyanik, Minara Shamkhalovna Shamkhalova, Marina Vladimirovna Shestakova
Format: Article
Language:English
Published: Endocrinology Research Centre 2015-06-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/6985
_version_ 1797255202724642816
author Igor Alexandrovich Sklyanik
Minara Shamkhalovna Shamkhalova
Marina Vladimirovna Shestakova
author_facet Igor Alexandrovich Sklyanik
Minara Shamkhalovna Shamkhalova
Marina Vladimirovna Shestakova
author_sort Igor Alexandrovich Sklyanik
collection DOAJ
description This review presents an analysis of clinical and experimental studies related to post-transplantation diabetes mellitus (PTDM) ? a specific complication after solid organ transplantation. A search of the databases eLibrary, PubMed and Scopus using the keywords ?posttransplantation diabetes mellitus?, ?new onset diabetes after transplantation?, ?transplantation? and ?immunosuppression? yielded in 523 results, including four from Russian literature (one original research manuscript). The analysis included original research, reviews, meta-analyses and monographs published not before 2005 in Russian and English. A total of 60 relevant original researches and reviews were included in this review. Diagnostic criteria, disease risk factors and potential pathogenic mechanisms were all considered. The mechanisms of the diabetogenic effect of modern immunosuppressive drugs were analysed. The principles of pre- and post-transplantation screening for PTDM and optimal management strategies for patients with PTDM are presented. The current controversial issues concerning the various aspects of PTDM are discussed.
first_indexed 2024-03-08T15:21:08Z
format Article
id doaj.art-47e04ff0cda6403e895bb47904669262
institution Directory Open Access Journal
issn 2072-0351
2072-0378
language English
last_indexed 2024-04-24T22:02:06Z
publishDate 2015-06-01
publisher Endocrinology Research Centre
record_format Article
series Сахарный диабет
spelling doaj.art-47e04ff0cda6403e895bb479046692622024-03-20T11:48:00ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782015-06-01182203110.14341/DM2015220-316771Post-transplantation diabetes mellitus: an overviewIgor Alexandrovich Sklyanik0Minara Shamkhalovna Shamkhalova1Marina Vladimirovna Shestakova2Endocrinology Research Centre, MoscowEndocrinology Research Centre, MoscowEndocrinology Research Centre, Moscow; Sechenov First Moscow State Medical University, MoscowThis review presents an analysis of clinical and experimental studies related to post-transplantation diabetes mellitus (PTDM) ? a specific complication after solid organ transplantation. A search of the databases eLibrary, PubMed and Scopus using the keywords ?posttransplantation diabetes mellitus?, ?new onset diabetes after transplantation?, ?transplantation? and ?immunosuppression? yielded in 523 results, including four from Russian literature (one original research manuscript). The analysis included original research, reviews, meta-analyses and monographs published not before 2005 in Russian and English. A total of 60 relevant original researches and reviews were included in this review. Diagnostic criteria, disease risk factors and potential pathogenic mechanisms were all considered. The mechanisms of the diabetogenic effect of modern immunosuppressive drugs were analysed. The principles of pre- and post-transplantation screening for PTDM and optimal management strategies for patients with PTDM are presented. The current controversial issues concerning the various aspects of PTDM are discussed.https://www.dia-endojournals.ru/jour/article/view/6985post-transplantation diabetes mellitustransplantationnew onset diabetesimmunosuppressive agentscytochrome p-450hypoglycaemic agents
spellingShingle Igor Alexandrovich Sklyanik
Minara Shamkhalovna Shamkhalova
Marina Vladimirovna Shestakova
Post-transplantation diabetes mellitus: an overview
Сахарный диабет
post-transplantation diabetes mellitus
transplantation
new onset diabetes
immunosuppressive agents
cytochrome p-450
hypoglycaemic agents
title Post-transplantation diabetes mellitus: an overview
title_full Post-transplantation diabetes mellitus: an overview
title_fullStr Post-transplantation diabetes mellitus: an overview
title_full_unstemmed Post-transplantation diabetes mellitus: an overview
title_short Post-transplantation diabetes mellitus: an overview
title_sort post transplantation diabetes mellitus an overview
topic post-transplantation diabetes mellitus
transplantation
new onset diabetes
immunosuppressive agents
cytochrome p-450
hypoglycaemic agents
url https://www.dia-endojournals.ru/jour/article/view/6985
work_keys_str_mv AT igoralexandrovichsklyanik posttransplantationdiabetesmellitusanoverview
AT minarashamkhalovnashamkhalova posttransplantationdiabetesmellitusanoverview
AT marinavladimirovnashestakova posttransplantationdiabetesmellitusanoverview