Comparison of prognostic scales for patients with metastatic spine disease
This is one-centre retrospective study with the aim to identify the scale, which provides the most accurate prediction of life expectancy in patients with metastatic lesions in spine. A retrospective analysis of clinical data of 138 patients with metastatic spinal tumors. Patients underwent spinal c...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Open Medical Publishing
2021-01-01
|
| Series: | Orthopedic Reviews |
| Subjects: | |
| Online Access: | https://www.pagepress.org/journals/index.php/or/article/view/8822 |
| _version_ | 1828139449220857856 |
|---|---|
| author | Anton Denisov Nikita S. Zaborovsky Dmitry A. Ptashnikov Dmitry A. Mikhailov Sergey V. Masevnin Oleg A. Smekalenkov |
| author_facet | Anton Denisov Nikita S. Zaborovsky Dmitry A. Ptashnikov Dmitry A. Mikhailov Sergey V. Masevnin Oleg A. Smekalenkov |
| author_sort | Anton Denisov |
| collection | DOAJ |
| description | This is one-centre retrospective study with the aim to identify the scale, which provides the most accurate prediction of life expectancy in patients with metastatic lesions in spine. A retrospective analysis of clinical data of 138 patients with metastatic spinal tumors. Patients underwent spinal cord decompression and instrumented stabilization of affected area. We evaluated the general condition according to the Karnofsky and ECOG scales, the presence of metastases in the visceral organs, spine and other bones, the neurological status and conduction of the medical therapy before spinal surgery. Observed clinical parameters were converted to Tokuhashi, Tomita, and Katagiri scales. For statistical analysis, software environment R 3.4.1 was used. Assessment of prognostic accuracy was performed using ROC analysis. The Tokuhashi scale showed AUC 0.605 (95% CI 0.586-0.616), Tomita scale showed AUC 0.708 (95% CI 0.573-0.842), Katagiri scale showed AUC 0.650 (95% CI 0.508-0.792). The best results for survival rate predicting after surgical treatment for metastatic spinal lesions were shown the Tomita scale. |
| first_indexed | 2024-04-11T18:51:40Z |
| format | Article |
| id | doaj.art-47e2312738a64150a27b587224d3fc27 |
| institution | Directory Open Access Journal |
| issn | 2035-8237 2035-8164 |
| language | English |
| last_indexed | 2024-04-11T18:51:40Z |
| publishDate | 2021-01-01 |
| publisher | Open Medical Publishing |
| record_format | Article |
| series | Orthopedic Reviews |
| spelling | doaj.art-47e2312738a64150a27b587224d3fc272022-12-22T04:08:19ZengOpen Medical PublishingOrthopedic Reviews2035-82372035-81642021-01-0112410.4081/or.2020.8822Comparison of prognostic scales for patients with metastatic spine diseaseAnton Denisov0Nikita S. Zaborovsky1Dmitry A. Ptashnikov2Dmitry A. Mikhailov3Sergey V. Masevnin4Oleg A. Smekalenkov5National Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. PetersburgNational Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. PetersburgNational Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. Petersburg; Mechnikov North-Western State Medical University, St. PetersburgNational Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. PetersburgNational Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. PetersburgNational Medical Research Center of Traumatology and Orthopedics n.a. Vreden R.R., St. PetersburgThis is one-centre retrospective study with the aim to identify the scale, which provides the most accurate prediction of life expectancy in patients with metastatic lesions in spine. A retrospective analysis of clinical data of 138 patients with metastatic spinal tumors. Patients underwent spinal cord decompression and instrumented stabilization of affected area. We evaluated the general condition according to the Karnofsky and ECOG scales, the presence of metastases in the visceral organs, spine and other bones, the neurological status and conduction of the medical therapy before spinal surgery. Observed clinical parameters were converted to Tokuhashi, Tomita, and Katagiri scales. For statistical analysis, software environment R 3.4.1 was used. Assessment of prognostic accuracy was performed using ROC analysis. The Tokuhashi scale showed AUC 0.605 (95% CI 0.586-0.616), Tomita scale showed AUC 0.708 (95% CI 0.573-0.842), Katagiri scale showed AUC 0.650 (95% CI 0.508-0.792). The best results for survival rate predicting after surgical treatment for metastatic spinal lesions were shown the Tomita scale.https://www.pagepress.org/journals/index.php/or/article/view/8822Spinal tumors; metastasis; Tomita scale; Tokuhashi scale; Katagiri scale |
| spellingShingle | Anton Denisov Nikita S. Zaborovsky Dmitry A. Ptashnikov Dmitry A. Mikhailov Sergey V. Masevnin Oleg A. Smekalenkov Comparison of prognostic scales for patients with metastatic spine disease Orthopedic Reviews Spinal tumors; metastasis; Tomita scale; Tokuhashi scale; Katagiri scale |
| title | Comparison of prognostic scales for patients with metastatic spine disease |
| title_full | Comparison of prognostic scales for patients with metastatic spine disease |
| title_fullStr | Comparison of prognostic scales for patients with metastatic spine disease |
| title_full_unstemmed | Comparison of prognostic scales for patients with metastatic spine disease |
| title_short | Comparison of prognostic scales for patients with metastatic spine disease |
| title_sort | comparison of prognostic scales for patients with metastatic spine disease |
| topic | Spinal tumors; metastasis; Tomita scale; Tokuhashi scale; Katagiri scale |
| url | https://www.pagepress.org/journals/index.php/or/article/view/8822 |
| work_keys_str_mv | AT antondenisov comparisonofprognosticscalesforpatientswithmetastaticspinedisease AT nikitaszaborovsky comparisonofprognosticscalesforpatientswithmetastaticspinedisease AT dmitryaptashnikov comparisonofprognosticscalesforpatientswithmetastaticspinedisease AT dmitryamikhailov comparisonofprognosticscalesforpatientswithmetastaticspinedisease AT sergeyvmasevnin comparisonofprognosticscalesforpatientswithmetastaticspinedisease AT olegasmekalenkov comparisonofprognosticscalesforpatientswithmetastaticspinedisease |