The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait Speed
Introduction: Exercise tolerance, an important factor affecting life prognosis and rehospitalization in patients with chronic heart failure, is a major outcome of cardiac rehabilitation. Heart failure with preserved ejection fraction (HFpEF) from reduced diastolic capacity has recently increased am...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2024-01-01
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| Series: | Journal of Modern Rehabilitation |
| Subjects: | |
| Online Access: | https://jmr.tums.ac.ir/index.php/jmr/article/view/738 |
| _version_ | 1827347962689224704 |
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| author | Masaki Takeyoshi Wakana Togami Kei Hiyama Seiji Takashio Yuichiro Arima Kenichi Tsujita Takeshi Miyamoto |
| author_facet | Masaki Takeyoshi Wakana Togami Kei Hiyama Seiji Takashio Yuichiro Arima Kenichi Tsujita Takeshi Miyamoto |
| author_sort | Masaki Takeyoshi |
| collection | DOAJ |
| description |
Introduction: Exercise tolerance, an important factor affecting life prognosis and rehospitalization in patients with chronic heart failure, is a major outcome of cardiac rehabilitation. Heart failure with preserved ejection fraction (HFpEF) from reduced diastolic capacity has recently increased among patients with chronic heart failure. This study evaluated and clarified the factors indicating exercise tolerance in patients with HFpEF from various perspectives, including cardiac and skeletal muscle functions.
Material and Methods: The subjects were 31 patients with HFpEF who underwent cardiac rehabilitation. Exercise tolerance was assessed using a 6-minute walking test. Physical function, physical activity, body composition test, baseline characteristics, blood data, and echocardiography results were extracted from medical records to identify the indicators of exercise tolerance.
Results: Gait speed was significantly different in exercise tolerance for HFpEF patients (β=0.75, p<0.01). Unlike HFrEF, HFpEF were no significant differences in brain natriuretic peptide (BNP) levels and cardiac function.
Conclusion: Gait speed is an indicator of exercise tolerance in HFpEF patients. However, its pathological course differs from HFrEF, indicating that it is poorly related to BNP, a biomarker for heart failure and cardiac function.
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| first_indexed | 2024-03-08T00:01:45Z |
| format | Article |
| id | doaj.art-47ef4cba59f14bfc9791c6924c4109c8 |
| institution | Directory Open Access Journal |
| issn | 2538-385X 2538-3868 |
| language | English |
| last_indexed | 2024-03-08T00:01:45Z |
| publishDate | 2024-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Modern Rehabilitation |
| spelling | doaj.art-47ef4cba59f14bfc9791c6924c4109c82024-02-18T04:09:23ZengTehran University of Medical SciencesJournal of Modern Rehabilitation2538-385X2538-38682024-01-0118110.18502/jmr.v18i1.14734The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait SpeedMasaki Takeyoshi0Wakana Togami1Kei Hiyama2Seiji Takashio3Yuichiro Arima4Kenichi Tsujita5Takeshi Miyamoto6Division of Rehabilitation Technology, Department of Medical Technology, Kumamoto University Hospital, Kumamoto, Japan.Department of Physical Medicine and Rehabilitation, Kumamoto University Hospital, Kumamoto, Japan.Department of Physical Medicine and Rehabilitation, Kumamoto University Hospital, Kumamoto, Japan.Department of Cardiovascular Medicine, Kumamoto University Hospital, Kumamoto, Japan.Department of Cardiovascular Medicine, Kumamoto University Hospital, Kumamoto, Japan.Department of Cardiovascular Medicine, Kumamoto University Hospital, Kumamoto, Japan.Department of Physical Medicine and Rehabilitation, Kumamoto University Hospital, Kumamoto, Japan. Introduction: Exercise tolerance, an important factor affecting life prognosis and rehospitalization in patients with chronic heart failure, is a major outcome of cardiac rehabilitation. Heart failure with preserved ejection fraction (HFpEF) from reduced diastolic capacity has recently increased among patients with chronic heart failure. This study evaluated and clarified the factors indicating exercise tolerance in patients with HFpEF from various perspectives, including cardiac and skeletal muscle functions. Material and Methods: The subjects were 31 patients with HFpEF who underwent cardiac rehabilitation. Exercise tolerance was assessed using a 6-minute walking test. Physical function, physical activity, body composition test, baseline characteristics, blood data, and echocardiography results were extracted from medical records to identify the indicators of exercise tolerance. Results: Gait speed was significantly different in exercise tolerance for HFpEF patients (β=0.75, p<0.01). Unlike HFrEF, HFpEF were no significant differences in brain natriuretic peptide (BNP) levels and cardiac function. Conclusion: Gait speed is an indicator of exercise tolerance in HFpEF patients. However, its pathological course differs from HFrEF, indicating that it is poorly related to BNP, a biomarker for heart failure and cardiac function. https://jmr.tums.ac.ir/index.php/jmr/article/view/738Exercise Tolerance, Gait Speed, Heart Failure |
| spellingShingle | Masaki Takeyoshi Wakana Togami Kei Hiyama Seiji Takashio Yuichiro Arima Kenichi Tsujita Takeshi Miyamoto The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait Speed Journal of Modern Rehabilitation Exercise Tolerance, Gait Speed, Heart Failure |
| title | The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait Speed |
| title_full | The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait Speed |
| title_fullStr | The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait Speed |
| title_full_unstemmed | The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait Speed |
| title_short | The Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction is Gait Speed |
| title_sort | index of exercise tolerance in heart failure with preserved ejection fraction is gait speed |
| topic | Exercise Tolerance, Gait Speed, Heart Failure |
| url | https://jmr.tums.ac.ir/index.php/jmr/article/view/738 |
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