The Preventive Effect of Decorin on Epidural Fibrosis and Epidural Adhesions After Laminectomy

The Preventive Effect of Decorin on Epidural Fibrosis and Epidural Adhesions After Laminectomy

Laminectomy is commonly performed to treat degenerative spinal diseases by reducing compression on the spinal cord and nerve roots. The postoperative epidural fibrosis and epidural adhesions may result in failed back surgery syndrome, which is characterized by the symptoms of lower back pain or leg...

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Bibliographic Details
Main Authors: Qing Ding, Qi Wei, Gaohong Sheng, Shanxi Wang, Shaoze Jing, Tian Ma, Ruizhuo Zhang, Tianqi Wang, Wenkai Li, Xiangyu Tang, Hua Wu, Chaoxu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
decorin
laminectomy
fibroblast
epidural fibrosis
epidural adhesion
Smad2/3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.774316/full

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