The ion channel TRPV5 regulates B-cell signaling and activation

The ion channel TRPV5 regulates B-cell signaling and activation

IntroductionB-cell activation triggers the release of endoplasmic reticulum calcium stores through the store-operated calcium entry (SOCE) pathway resulting in calcium influx by calcium release-activated calcium (CRAC) channels on the plasma membrane. B-cell-specific murine knockouts of SOCE do not...

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Bibliographic Details
Main Authors: Trisha Mahtani, Hena Sheth, L. K. Smith, Leshawn Benedict, Aurelie Brecier, Nader Ghasemlou, Bebhinn Treanor
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
B cells
signaling
TRPV5
ion channels
transient receptor potential channel
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1386719/full

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