VPS35 and the mitochondria: Connecting the dots in Parkinson's disease pathophysiology
Mutations in VPS35 (PARK17), a key molecule in the retromer complex, are a rare cause of autosomal dominant Parkinson's disease (PD), the second most common neurodegenerative disorder. VPS35 exerts crucial functions within the cell in terms of regulating endosomal trafficking. However new data...
Main Authors: | Gianni Cutillo, David K. Simon, Simona Eleuteri |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996120303314 |
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