Agomelatine prevented depression in the chronic restraint stress model through enhanced catalase activity and halted oxidative stress.

Agomelatine prevented depression in the chronic restraint stress model through enhanced catalase activity and halted oxidative stress.

<h4>Background</h4>Agomelatine (AGO) is an antidepressant with unique pharmacological effects; however, its underlying mechanisms remain unknown. In this study, we examined agomelatine's effects on catalase activity, oxidative stress, and inflammation.<h4>Methods</h4>Chr...

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Bibliographic Details
Main Authors: Jiaxi Xu, Cheng Zhu, Piaopiao Jin, Wangdi Sun, Enyan Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0289248&type=printable

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