Associations of Polymorphisms Localized in the 3′UTR Regions of the <i>KRAS</i>, <i>NRAS</i>, <i>MAPK1</i> Genes with Laryngeal Squamous Cell Carcinoma

Associations of Polymorphisms Localized in the 3′UTR Regions of the <i>KRAS</i>, <i>NRAS</i>, <i>MAPK1</i> Genes with Laryngeal Squamous Cell Carcinoma

Background: Genetic variations, localized in the 3′ untranslated region (UTR) in mitogen-activated protein kinase (MAPK) pathway-related genes, may alter the transcription and impact the pathogenesis of laryngeal squamous cell carcinoma (LSCC). The present study investigated the associations of sing...

Full description

Bibliographic Details
Main Authors:	Ruta Insodaite, Alina Smalinskiene, Vykintas Liutkevicius, Virgilijus Ulozas, Roberta Poceviciute, Arunas Bielevicius, Laimutis Kucinskas
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Series:	Genes
Subjects:	laryngeal squamous cell carcinoma single-nucleotide polymorphisms mitogen-activated protein kinases <i>KRAS</i> <i>NRAS</i> <i>MAPK1</i>
Online Access:	https://www.mdpi.com/2073-4425/12/11/1679

Similar Items

<i>KRAS, NRAS, BRAF, HER2</i> and MSI Status in a Large Consecutive Series of Colorectal Carcinomas
by: Aleksandr S. Martianov, et al.
Published: (2023-03-01)

Atypical <i>BRAF</i> and <i>NRAS</i> Mutations in Mucosal Melanoma
by: Nicolas Dumaz, et al.
Published: (2019-08-01)

Prognostic Roles of <i>BRAF</i>, <i>KIT</i>, <i>NRAS</i>, <i>IGF2R</i> and <i>SF3B1</i> Mutations in Mucosal Melanomas
by: Joanna P. Wróblewska, et al.
Published: (2021-08-01)

Evaluation of <i>RAS</i> Mutational Status in Liquid Biopsy to Monitor Disease Progression in Metastatic Colorectal Cancer Patients
by: Elena Lastraioli, et al.
Published: (2023-05-01)

Imaging Mass Spectrometry for the Classification of Melanoma Based on <i>BRAF</i>/<i>NRAS</i> Mutational Status
by: Rita Casadonte, et al.
Published: (2023-03-01)

Association of CX36 Protein Encoding Gene <i>GJD2</i> with Refractive Errors
by: Edita Kunceviciene, et al.
Published: (2022-06-01)

A Critical Review of the Prognostic and Predictive Implications of <i>KRAS</i> and <i>STK11</i> Mutations and Co-Mutations in Metastatic Non-Small Lung Cancer
by: Peter Manolakos, et al.
Published: (2023-06-01)

Determination of the Prevalence of Microsatellite Instability, <i>BRAF</i> and <i>KRAS</i>/<i>NRAS</i> Mutation Status in Patients with Colorectal Cancer in Slovakia
by: Tomas Rendek, et al.
Published: (2024-03-01)

Clinicopathological Characteristics and Mutational Landscape of <i>APC</i>, <i>HOXB13,</i> and <i>KRAS</i> among Rwandan Patients with Colorectal Cancer
by: Felix Manirakiza, et al.
Published: (2023-05-01)

Prognostic Value of <i>KRAS</i> Mutations in Colorectal Cancer Patients
by: Asimina Koulouridi, et al.
Published: (2022-07-01)

<i>KRAS</i> and <i>BRAF</i> Mutation Rates and Survival Outcomes in Colorectal Cancer in an Ethnically Diverse Patient Cohort
by: Paul Habashy, et al.
Published: (2023-12-01)

Pulmonary Adenocarcinoma In Situ and Minimally Invasive Adenocarcinomas in European Patients Have Less <i>KRAS</i> and More <i>EGFR</i> Mutations Compared to Advanced Adenocarcinomas
by: Jennie Petterson, et al.
Published: (2024-03-01)

Identification of <i>NRAS</i> Diagnostic Biomarkers and Drug Targets for Endometrial Cancer—An Integrated in Silico Approach
by: Larsen Alessandro, et al.
Published: (2022-11-01)

Targeting <i>KRAS</i> in Cancer: Promising Therapeutic Strategies
by: Lisa Maria Mustachio, et al.
Published: (2021-03-01)

Association of <i>KRAS</i> G12C Status with Age at Onset of Metastatic Colorectal Cancer
by: Marcelo Sunagua Aruquipa, et al.
Published: (2024-02-01)

<i>KRAS</i> Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer
by: Ella A. Eklund, et al.
Published: (2022-04-01)

FREQUENCY OF NRAS AND KRAS GENES IN NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA PATIENTS
by: Sidra Barlas, et al.
Published: (2020-04-01)

<i>KRAS</i> and <i>BRAF</i> Mutations as Prognostic and Predictive Biomarkers for Standard Chemotherapy Response in Metastatic Colorectal Cancer: A Single Institutional Study
by: Nuria Garcia-Carbonero, et al.
Published: (2020-01-01)

Direct Targeting <i>KRAS</i> Mutation in Non-Small Cell Lung Cancer: Focus on Resistance
by: Damien Reita, et al.
Published: (2022-03-01)

Crucial Role of Oncogenic <i>KRAS</i> Mutations in Apoptosis and Autophagy Regulation: Therapeutic Implications
by: Anabela Ferreira, et al.
Published: (2022-07-01)

KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma
by: Sergiu Pasca, et al.
Published: (2019-10-01)

NRAS and KRAS polymorphisms are not associated with hepatoblastoma susceptibility in Chinese children
by: Tianyou Yang, et al.
Published: (2019-05-01)

Relationship between KRAS and NRAS factors with clinicopathologic findings in patients with metastatic colon cancer
by: Hamid Saeidi Saedi, et al.
Published: (2023-03-01)

<i>KRAS</i>-Mutant Non-Small-Cell Lung Cancer: From Past Efforts to Future Challenges
by: Serena Ceddia, et al.
Published: (2022-08-01)

<i>KRAS</i> Mutation Status in Bulgarian Patients with Advanced and Metastatic Colorectal Cancer
by: Maria Radanova, et al.
Published: (2023-08-01)

CT-Based Radiomics to Predict <i>KRAS</i> Mutation in CRC Patients Using a Machine Learning Algorithm: A Retrospective Study
by: Jacobo Porto-Álvarez, et al.
Published: (2023-07-01)

Correlation between <i>KRAS</i> Mutation and <i>CTLA-4</i> mRNA Expression in Circulating Tumour Cells: Clinical Implications in Colorectal Cancer
by: Sharmin Aktar, et al.
Published: (2023-09-01)

Mitochondrial Respiration in <i>KRAS</i> and <i>BRAF</i> Mutated Colorectal Tumors and Polyps
by: Egle Rebane-Klemm, et al.
Published: (2020-03-01)

Novel <i>Antrodia cinnamomea</i> Extract Reduced Cancer Stem-Like Phenotype Changes and Resensitized <i>KRAS</i>-Mutant Colorectal Cancer via a MicroRNA-27a Pathway
by: Tsung-Jen Lin, et al.
Published: (2019-10-01)

The Prognostic Effect of <i>KRAS</i> Mutations in Non-Small Cell Lung Carcinoma Revisited: A Norwegian Multicentre Study
by: Sissel Gyrid Freim Wahl, et al.
Published: (2021-08-01)

Molecular Divergence upon <i>EGFR</i>-TKI Resistance Could Be Dependent on the Exon Location of the Original <i>EGFR</i>-Sensitizing Mutation
by: Roberto Serna-Blasco, et al.
Published: (2022-09-01)

Active Compound of <i>Pharbitis</i> Semen (<i>Pharbitis nil</i> Seeds) Suppressed KRAS-Driven Colorectal Cancer and Restored Muscle Cell Function during Cancer Progression
by: Jisu Song, et al.
Published: (2020-06-01)

Noncoding RNA Profile in Reovirus Treated <i>KRAS</i>-Mutated Colorectal Cancer Patients
by: Rafael Saperstein, et al.
Published: (2023-10-01)

Correlation between KRAS, NRAS and BRAF mutations and tumor localizations in patients with primary and metastatic colorectal cancer
by: Aleksandra Bożyk, et al.
Published: (2021-03-01)

The role of KRAS and NRAS mutation detection in determining the therapy strategy for colorectal cancer
by: A. N. Toropovskiy, et al.
Published: (2022-11-01)

Protein Arginine Methyltransferase 5 as a Therapeutic Target for <i>KRAS</i> Mutated Colorectal Cancer
by: David Shifteh, et al.
Published: (2020-07-01)

<i>KRAS</i> Mutational Profiles among Colorectal Cancer Patients in the East Coast of Peninsular Malaysia
by: Hidayati Husainy Hasbullah, et al.
Published: (2023-02-01)

Efficacy of Immunotherapy in Second-Line Treatment of <i>KRAS</i>-Mutated Patients with Non-Small-Cell Lung Cancer—Data from Daily Practice
by: Magdalena Knetki-Wróblewska, et al.
Published: (2022-12-01)

Prognostic Role of <i>KRAS G12C</i> Mutation in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis
by: Durgesh Wankhede, et al.
Published: (2023-09-01)

Target-Specific Nanoparticle Polyplex Down-Regulates Mutant <i>Kras</i> to Prevent Pancreatic Carcinogenesis and Halt Tumor Progression
by: Jill P. Smith, et al.
Published: (2023-01-01)