Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases
Hydrophilic polymers are commonly used as coatings on intravascular medical devices. As intravascular pro-cedures continue to increase in frequency, the risk of embolization of this material throughout the body has become evident. These emboli may be discovered incidentally but can result in serious...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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University of Münster / Open Journals System
2021-09-01
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| Series: | Free Neuropathology |
| Subjects: | |
| Online Access: | https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/3457 |
| _version_ | 1818906415154069504 |
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| author | Vanessa S. Goodwill Michael G. Brandel Jeffrey A. Steinberg Thomas L. Beaumont Lawrence A. Hansen |
| author_facet | Vanessa S. Goodwill Michael G. Brandel Jeffrey A. Steinberg Thomas L. Beaumont Lawrence A. Hansen |
| author_sort | Vanessa S. Goodwill |
| collection | DOAJ |
| description | Hydrophilic polymers are commonly used as coatings on intravascular medical devices. As intravascular pro-cedures continue to increase in frequency, the risk of embolization of this material throughout the body has become evident. These emboli may be discovered incidentally but can result in serious complications includ-ing death. Here, we report the first two cases of hydrophilic polymer embolism (HPE) identified on brain tu-mor resection following Wada testing. One patient experienced multifocal vascular complications and diffuse cerebral edema, while the other had an uneventful postoperative course. Wada testing is frequently per-formed during preoperative planning prior to epilepsy surgery or the resection of tumors in eloquent brain regions. These cases demonstrate the need for increased recognition of this histologic finding to enable fur-ther correlation with clinical outcomes. |
| first_indexed | 2024-12-19T21:38:52Z |
| format | Article |
| id | doaj.art-4802239957d94d8e892cc0d3c653add4 |
| institution | Directory Open Access Journal |
| issn | 2699-4445 |
| language | English |
| last_indexed | 2024-12-19T21:38:52Z |
| publishDate | 2021-09-01 |
| publisher | University of Münster / Open Journals System |
| record_format | Article |
| series | Free Neuropathology |
| spelling | doaj.art-4802239957d94d8e892cc0d3c653add42022-12-21T20:04:42ZengUniversity of Münster / Open Journals SystemFree Neuropathology2699-44452021-09-01210.17879/freeneuropathology-2021-3457Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 casesVanessa S. Goodwill0Michael G. Brandel1Jeffrey A. Steinberg2Thomas L. Beaumont3Lawrence A. Hansen4Department of Pathology, University of California, San DiegoDepartment of Neurosurgery, University of California, San DiegoDepartment of Neurosurgery, University of California, San DiegoDepartment of Neurosurgery, University of California, San DiegoDepartment of Pathology, University of California, San DiegoHydrophilic polymers are commonly used as coatings on intravascular medical devices. As intravascular pro-cedures continue to increase in frequency, the risk of embolization of this material throughout the body has become evident. These emboli may be discovered incidentally but can result in serious complications includ-ing death. Here, we report the first two cases of hydrophilic polymer embolism (HPE) identified on brain tu-mor resection following Wada testing. One patient experienced multifocal vascular complications and diffuse cerebral edema, while the other had an uneventful postoperative course. Wada testing is frequently per-formed during preoperative planning prior to epilepsy surgery or the resection of tumors in eloquent brain regions. These cases demonstrate the need for increased recognition of this histologic finding to enable fur-ther correlation with clinical outcomes.https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/3457EmbolismVascular access devicesBrain infarctionGliomaVasculitis |
| spellingShingle | Vanessa S. Goodwill Michael G. Brandel Jeffrey A. Steinberg Thomas L. Beaumont Lawrence A. Hansen Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases Free Neuropathology Embolism Vascular access devices Brain infarction Glioma Vasculitis |
| title | Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases |
| title_full | Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases |
| title_fullStr | Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases |
| title_full_unstemmed | Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases |
| title_short | Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases |
| title_sort | hydrophilic polymer embolism identified in brain tumor specimens following wada testing a report of 2 cases |
| topic | Embolism Vascular access devices Brain infarction Glioma Vasculitis |
| url | https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/3457 |
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