The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazide
This article discusses the definition, classification and pathogenetic mechanisms of cognitive functions in arterial hypertension. The authors discuss the capabilities of the different classes of antihypertensive drugs in correction of cognitive impairments and prevention of dementia. The authors al...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Morozov P.V.
2016-12-01
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| Series: | Системные гипертензии |
| Subjects: | |
| Online Access: | https://syst-hypertension.ru/2075-082X/article/viewFile/29158/pdf |
| _version_ | 1818536989640622080 |
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| author | O D Ostroumova I A Garelik E A Karavashkina |
| author_facet | O D Ostroumova I A Garelik E A Karavashkina |
| author_sort | O D Ostroumova |
| collection | DOAJ |
| description | This article discusses the definition, classification and pathogenetic mechanisms of cognitive functions in arterial hypertension. The authors discuss the capabilities of the different classes of antihypertensive drugs in correction of cognitive impairments and prevention of dementia. The authors also discuss the advantages of the angiotensin II receptor blockers in prevention of dementia and in their potential mechanisms of cerebral protection. The article describes in detail the possibilities of valsartan in correction of cognitive impairments associated with arterial hypertension, the advantages of valsartan in comparison with calcium antagonists and its unique neuroprotective mechanisms. We show our own results of the study concerning fixed-dose combination of valsartan and hydrochlorothiazide, and find out that this combination has high antihypertensive and cerebral protection (capacity to improve cognitive function) and effectiveness. |
| first_indexed | 2024-12-11T18:44:58Z |
| format | Article |
| id | doaj.art-480a321b8f4a4596a282c08101ce805e |
| institution | Directory Open Access Journal |
| issn | 2075-082X 2542-2189 |
| language | Russian |
| last_indexed | 2024-12-11T18:44:58Z |
| publishDate | 2016-12-01 |
| publisher | IP Morozov P.V. |
| record_format | Article |
| series | Системные гипертензии |
| spelling | doaj.art-480a321b8f4a4596a282c08101ce805e2022-12-22T00:54:29ZrusIP Morozov P.V.Системные гипертензии2075-082X2542-21892016-12-01134475526259The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazideO D Ostroumova0I A Garelik1E A Karavashkina2A.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation; I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationA.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian FederationA.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian FederationThis article discusses the definition, classification and pathogenetic mechanisms of cognitive functions in arterial hypertension. The authors discuss the capabilities of the different classes of antihypertensive drugs in correction of cognitive impairments and prevention of dementia. The authors also discuss the advantages of the angiotensin II receptor blockers in prevention of dementia and in their potential mechanisms of cerebral protection. The article describes in detail the possibilities of valsartan in correction of cognitive impairments associated with arterial hypertension, the advantages of valsartan in comparison with calcium antagonists and its unique neuroprotective mechanisms. We show our own results of the study concerning fixed-dose combination of valsartan and hydrochlorothiazide, and find out that this combination has high antihypertensive and cerebral protection (capacity to improve cognitive function) and effectiveness.https://syst-hypertension.ru/2075-082X/article/viewFile/29158/pdfarterial hypertensioncognitive functionsdementiaantihypertensive therapyangiotensin ii receptor antagonistsvalsartanhydrochlorothiazidefixed-dose combinations of antihypertensive drugs |
| spellingShingle | O D Ostroumova I A Garelik E A Karavashkina The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazide Системные гипертензии arterial hypertension cognitive functions dementia antihypertensive therapy angiotensin ii receptor antagonists valsartan hydrochlorothiazide fixed-dose combinations of antihypertensive drugs |
| title | The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazide |
| title_full | The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazide |
| title_fullStr | The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazide |
| title_full_unstemmed | The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazide |
| title_short | The choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia: possibilities of valsartan and fixed-dose combination of valsartan and hydrochlorothiazide |
| title_sort | choice of antihypertensive therapy in correction of cognitive impairments and prevention of dementia possibilities of valsartan and fixed dose combination of valsartan and hydrochlorothiazide |
| topic | arterial hypertension cognitive functions dementia antihypertensive therapy angiotensin ii receptor antagonists valsartan hydrochlorothiazide fixed-dose combinations of antihypertensive drugs |
| url | https://syst-hypertension.ru/2075-082X/article/viewFile/29158/pdf |
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