Distinct patterns of cerebral extravasation by Evans blue and sodium fluorescein in rats.

Distinct patterns of cerebral extravasation by Evans blue and sodium fluorescein in rats.

The Evans blue dye (EBD; 961 Da) and the sodium fluorescein dye (NaF; 376 Da) are commonly used inert tracers in blood-brain barrier (BBB) research. They are both highly charged low molecular weight (LMW) tracers with similar lipophobic profiles. Nevertheless, the EBD binds to serum albumin (69,000...

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Bibliographic Details
Main Authors: Lola Fenghuei Yen, Vivi Chiali Wei, Eva Yuhua Kuo, Ted Weita Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3702610?pdf=render

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