Vascular stiffness and diastolic heart failure
Vascular stiffness is regarded as a result of degenerative processes potentiated by aging, hypertension, and other risk factors. Central hemodynamic changes are one of the serious sequels of high arterial stiffness, which gives rise to a chain of events as a higher postload on the left ventricle, it...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2013-11-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31397 |
| _version_ | 1818437168405676032 |
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| author | O M Drapkina A N Kaburova |
| author_facet | O M Drapkina A N Kaburova |
| author_sort | O M Drapkina |
| collection | DOAJ |
| description | Vascular stiffness is regarded as a result of degenerative processes potentiated by aging, hypertension, and other risk factors. Central hemodynamic changes are one of the serious sequels of high arterial stiffness, which gives rise to a chain of events as a higher postload on the left ventricle, its concentric hypertrophy, diastolic dysfunction and increases the overall risk of cardiovascular events. The purpose of the review is to discuss the mechanisms of vascular stiffness, focusing on the role of this condition in the development of chronic heart failure with retained ejection fraction and its pathogenetic treatment as a future target. |
| first_indexed | 2024-12-14T17:20:23Z |
| format | Article |
| id | doaj.art-480d9bd65d8940eeacdd908ce1f788b8 |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-14T17:20:23Z |
| publishDate | 2013-11-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-480d9bd65d8940eeacdd908ce1f788b82022-12-21T22:53:20Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422013-11-018511758128413Vascular stiffness and diastolic heart failureO M DrapkinaA N KaburovaVascular stiffness is regarded as a result of degenerative processes potentiated by aging, hypertension, and other risk factors. Central hemodynamic changes are one of the serious sequels of high arterial stiffness, which gives rise to a chain of events as a higher postload on the left ventricle, its concentric hypertrophy, diastolic dysfunction and increases the overall risk of cardiovascular events. The purpose of the review is to discuss the mechanisms of vascular stiffness, focusing on the role of this condition in the development of chronic heart failure with retained ejection fraction and its pathogenetic treatment as a future target.https://ter-arkhiv.ru/0040-3660/article/view/31397vascular stiffnessdiastolic chronic heart failurefibrosisendothelial dysfunctioninflammation |
| spellingShingle | O M Drapkina A N Kaburova Vascular stiffness and diastolic heart failure Терапевтический архив vascular stiffness diastolic chronic heart failure fibrosis endothelial dysfunction inflammation |
| title | Vascular stiffness and diastolic heart failure |
| title_full | Vascular stiffness and diastolic heart failure |
| title_fullStr | Vascular stiffness and diastolic heart failure |
| title_full_unstemmed | Vascular stiffness and diastolic heart failure |
| title_short | Vascular stiffness and diastolic heart failure |
| title_sort | vascular stiffness and diastolic heart failure |
| topic | vascular stiffness diastolic chronic heart failure fibrosis endothelial dysfunction inflammation |
| url | https://ter-arkhiv.ru/0040-3660/article/view/31397 |
| work_keys_str_mv | AT omdrapkina vascularstiffnessanddiastolicheartfailure AT ankaburova vascularstiffnessanddiastolicheartfailure |