Lymphoblast Oxidative Stress Genes as Potential Biomarkers of Disease Severity and Drug Effect in Friedreich's Ataxia.

Lymphoblast Oxidative Stress Genes as Potential Biomarkers of Disease Severity and Drug Effect in Friedreich's Ataxia.

There is no current approved therapy for the ultimately lethal neuro- and cardio-degenerative disease Friedreich's ataxia (FA). Finding minimally-invasive molecular biomarkers of disease progression and drug effect could support smaller, shorter clinical trials. Since we and others have noted a...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Genki Hayashi, Gino Cortopassi
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	Public Library of Science (PLoS) 2016-01-01
Sraith:	PLoS ONE
Rochtain ar líne:	http://europepmc.org/articles/PMC4831832?pdf=render

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Genetics of Friedreich Ataxia
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Clinical and Genetic Diagnosis of Friedreich’s Ataxia
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Emerging antioxidant therapies in Friedreich’s ataxia
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An Overview of the Ferroptosis Hallmarks in Friedreich’s Ataxia
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Perspectives on current models of Friedreich’s ataxia
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Epigenetic-based therapies for Friedreich ataxia
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Hepatic mitochondrial dysfunction in Friedreich Ataxia
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