Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications
<i>Euphausia superba</i>, commonly known as krill, is a small marine crustacean from the Antarctic Ocean that plays an important role in the marine ecosystem, serving as feed for most fish. It is a known source of highly bioavailable omega-3 polyunsaturated fatty acids (eicosapentaenoic...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/19/6/306 |
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| author | Alessandro Colletti Giancarlo Cravotto Valentina Citi Alma Martelli Lara Testai Arrigo F. G. Cicero |
| author_facet | Alessandro Colletti Giancarlo Cravotto Valentina Citi Alma Martelli Lara Testai Arrigo F. G. Cicero |
| author_sort | Alessandro Colletti |
| collection | DOAJ |
| description | <i>Euphausia superba</i>, commonly known as krill, is a small marine crustacean from the Antarctic Ocean that plays an important role in the marine ecosystem, serving as feed for most fish. It is a known source of highly bioavailable omega-3 polyunsaturated fatty acids (eicosapentaenoic acid and docosahexaenoic acid). In preclinical studies, krill oil showed metabolic, anti-inflammatory, neuroprotective and chemo preventive effects, while in clinical trials it showed significant metabolic, vascular and ergogenic actions. Solvent extraction is the most conventional method to obtain krill oil. However, different solvents must be used to extract all lipids from krill because of the diversity of the polarities of the lipid compounds in the biomass. This review aims to provide an overview of the chemical composition, bioavailability and bioaccessibility of krill oil, as well as the mechanisms of action, classic and non-conventional extraction techniques, health benefits and current applications of this marine crustacean. |
| first_indexed | 2024-03-10T11:02:19Z |
| format | Article |
| id | doaj.art-480ea9a88d3a4d438feeebfdf78d8d64 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-10T11:02:19Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-480ea9a88d3a4d438feeebfdf78d8d642023-11-21T21:23:14ZengMDPI AGMarine Drugs1660-33972021-05-0119630610.3390/md19060306Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical ApplicationsAlessandro Colletti0Giancarlo Cravotto1Valentina Citi2Alma Martelli3Lara Testai4Arrigo F. G. Cicero5Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyDepartment of Drug Science and Technology, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyDepartment of Pharmacy, University of Pisa, 56121 Pisa, ItalyDepartment of Pharmacy, University of Pisa, 56121 Pisa, ItalyDepartment of Pharmacy, University of Pisa, 56121 Pisa, ItalyMedical and Surgical Sciences Department, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy<i>Euphausia superba</i>, commonly known as krill, is a small marine crustacean from the Antarctic Ocean that plays an important role in the marine ecosystem, serving as feed for most fish. It is a known source of highly bioavailable omega-3 polyunsaturated fatty acids (eicosapentaenoic acid and docosahexaenoic acid). In preclinical studies, krill oil showed metabolic, anti-inflammatory, neuroprotective and chemo preventive effects, while in clinical trials it showed significant metabolic, vascular and ergogenic actions. Solvent extraction is the most conventional method to obtain krill oil. However, different solvents must be used to extract all lipids from krill because of the diversity of the polarities of the lipid compounds in the biomass. This review aims to provide an overview of the chemical composition, bioavailability and bioaccessibility of krill oil, as well as the mechanisms of action, classic and non-conventional extraction techniques, health benefits and current applications of this marine crustacean.https://www.mdpi.com/1660-3397/19/6/306krill oilomega-3 polyunsaturated fatty acidsbioavailabilitynutraceuticalsdietary supplements |
| spellingShingle | Alessandro Colletti Giancarlo Cravotto Valentina Citi Alma Martelli Lara Testai Arrigo F. G. Cicero Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications Marine Drugs krill oil omega-3 polyunsaturated fatty acids bioavailability nutraceuticals dietary supplements |
| title | Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications |
| title_full | Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications |
| title_fullStr | Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications |
| title_full_unstemmed | Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications |
| title_short | Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications |
| title_sort | advances in technologies for highly active omega 3 fatty acids from krill oil clinical applications |
| topic | krill oil omega-3 polyunsaturated fatty acids bioavailability nutraceuticals dietary supplements |
| url | https://www.mdpi.com/1660-3397/19/6/306 |
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