Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson’s Disease
Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons from the substantia nigra (SN) that project to the dorsal striatum (caudate-putamen). To better understand the molecular mechanisms underlying PD, we performed combined lipid profiling and RNA sequencing of SN and putamen...
Main Authors: | Helena Xicoy, Jos F. Brouwers, Bé Wieringa, Gerard J. M. Martens |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/9/1966 |
Similar Items
-
KTN1 Variants Underlying Putamen Gray Matter Volumes and Parkinson’s Disease
by: Qiao Mao, et al.
Published: (2020-06-01) -
Ninetieth Anniversary of Parkinson’s Disease «Substantia Nigra» Theory
by: O.N. Voskresenskaya, et al.
Published: (2009-06-01) -
Altered expression of glycobiology-related genes in Parkinson’s disease brain
by: Jay S. Schneider, et al.
Published: (2022-11-01) -
The application value of quantitative susceptibility mapping in evaluating substantia nigra "swallow tail sign" in the diagnosis of Parkinson's disease
by: Xiao-jun GUAN, et al.
Published: (2018-04-01) -
Transcranial Sonographic Alterations of Substantia Nigra and Third Ventricle in Parkinson's Disease with or without Dementia
by: Zhi-Fen Dong, et al.
Published: (2017-01-01)