Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome)
Fundamental innovations in the study of the regulatory mechanisms of circulation in the past 20-30 years (evidence for the role of the endothelium in local hemodynamic control, the basic significance of the tissue (paracrine) link of the angiotensin mechanism of not only as a vasoconstrictor, but al...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2010-04-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/30555 |
| _version_ | 1819082410573168640 |
|---|---|
| author | Evgeniy Evgen'evich Gogin E E Gogin |
| author_facet | Evgeniy Evgen'evich Gogin E E Gogin |
| author_sort | Evgeniy Evgen'evich Gogin |
| collection | DOAJ |
| description | Fundamental innovations in the study of the regulatory mechanisms of circulation in the past 20-30 years (evidence for the role of the endothelium in local hemodynamic control, the basic significance of the tissue (paracrine) link of the angiotensin mechanism of not only as a vasoconstrictor, but also a trigger of a slow pressor component that leads to resistance bed arterial remodeling) have required the concept of the pathogenesis of hypertensive disease (HD) (essential hypertension) to be reconsidered, confirmed its qualificational (nosological) isolation (by the criterion of the presence of an attributive functional and structural sign). The new refined and concrete information on the pathogenesis of HD and its associated cardiovascular disease has shown to give doctors reliable landmarks to optimize drug therapy: both symptomatic (to accelerate effective blood pressure control) and basic (to eliminate endothelial dysfunction and to restore remodeled arteries and microcirculation) therapies. |
| first_indexed | 2024-12-21T20:16:14Z |
| format | Article |
| id | doaj.art-48131d32cef349d894bf7c447a4c734e |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-21T20:16:14Z |
| publishDate | 2010-04-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-48131d32cef349d894bf7c447a4c734e2022-12-21T18:51:35Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422010-04-0182451027582Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome)Evgeniy Evgen'evich GoginE E Gogin0Central Clinical Hospital with Polyclinic, Department for Presidential Affairs of the Russian FederationFundamental innovations in the study of the regulatory mechanisms of circulation in the past 20-30 years (evidence for the role of the endothelium in local hemodynamic control, the basic significance of the tissue (paracrine) link of the angiotensin mechanism of not only as a vasoconstrictor, but also a trigger of a slow pressor component that leads to resistance bed arterial remodeling) have required the concept of the pathogenesis of hypertensive disease (HD) (essential hypertension) to be reconsidered, confirmed its qualificational (nosological) isolation (by the criterion of the presence of an attributive functional and structural sign). The new refined and concrete information on the pathogenesis of HD and its associated cardiovascular disease has shown to give doctors reliable landmarks to optimize drug therapy: both symptomatic (to accelerate effective blood pressure control) and basic (to eliminate endothelial dysfunction and to restore remodeled arteries and microcirculation) therapies.https://ter-arkhiv.ru/0040-3660/article/view/30555hypertensive diseasepathogenesistreatment optimization |
| spellingShingle | Evgeniy Evgen'evich Gogin E E Gogin Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome) Терапевтический архив hypertensive disease pathogenesis treatment optimization |
| title | Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome) |
| title_full | Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome) |
| title_fullStr | Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome) |
| title_full_unstemmed | Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome) |
| title_short | Arterial hypertension and hypertensive disease (syndromic diagnosis and nosological syndrome) |
| title_sort | arterial hypertension and hypertensive disease syndromic diagnosis and nosological syndrome |
| topic | hypertensive disease pathogenesis treatment optimization |
| url | https://ter-arkhiv.ru/0040-3660/article/view/30555 |
| work_keys_str_mv | AT evgeniyevgenevichgogin arterialhypertensionandhypertensivediseasesyndromicdiagnosisandnosologicalsyndrome AT eegogin arterialhypertensionandhypertensivediseasesyndromicdiagnosisandnosologicalsyndrome |