Associations of ApoE4 status and DHA supplementation on plasma and CSF lipid profiles and entorhinal cortex thickness

Associations of ApoE4 status and DHA supplementation on plasma and CSF lipid profiles and entorhinal cortex thickness

Apolipoprotein ε allele 4 (APOE4) influences the metabolism of polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acid (DHA). The entorhinal cortex (EC) in the brain is affected early in Alzheimer's disease and is rich in DHA. The purpose of this study is to identify the effect of APOE...

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Bibliographic Details
Main Authors: Mikaila Ann Bantugan, Haotian Xian, Victoria Solomon, Mitchell Lee, Zhiheng Cai, Shaowei Wang, Marlon V. Duro, Bilal E. Kerman, Alfred Fonteh, Cristiana Meuret, Meitong Li, Meredith N. Braskie, Laura Beth J. McIntire, Lucia Jurin, Sarah Oberlin, James Evans, Roderick Davis, Wendy J. Mack, Laila Abdullah, Hussein N. Yassine
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Lipid Research
Subjects:
ApoE
Lipids
Brain
Alzheimer’s
Lipidomics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523000275

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