Human iPSC-Derived Renal Cells Change Their Immunogenic Properties during Maturation: Implications for Regenerative Therapies

Human iPSC-Derived Renal Cells Change Their Immunogenic Properties during Maturation: Implications for Regenerative Therapies

The success of human induced pluripotent stem cell (hiPSC)-based therapy critically depends on understanding and controlling the immunological effects of the hiPSC-derived transplant. While hiPSC-derived cells used for cell therapy are often immature with post-grafting maturation, immunological prop...

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Bibliographic Details
Main Authors: Bella Rossbach, Krithika Hariharan, Nancy Mah, Su-Jun Oh, Hans-Dieter Volk, Petra Reinke, Andreas Kurtz
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
human induced pluripotent stem cells
renal differentiation
cell replacement therapy
HLA barrier
Online Access:https://www.mdpi.com/2073-4409/11/8/1328

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