DNA Damage Inducer Mitoxantrone Amplifies Synergistic Mild‐Photothermal Chemotherapy for TNBC via Decreasing Heat Shock Protein 70 Expression

DNA Damage Inducer Mitoxantrone Amplifies Synergistic Mild‐Photothermal Chemotherapy for TNBC via Decreasing Heat Shock Protein 70 Expression

Abstract Patients with triple‐negative breast cancer (TNBC) have the worst clinical outcomes when compared to other subtypes of breast cancer. Nanotechnology‐assisted photothermal therapy (PTT) opens new opportunities for precise cancer treatment. However, thermoresistance caused by PTT, as well as...

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Bibliographic Details
Main Authors: Zuqin Chen, Sunfan Li, Fangzhou Li, Cheng Qin, Xianlei Li, Guangchao Qing, Jinjin Wang, Bozhang Xia, Fuxue Zhang, Liangliang Meng, Xing‐Jie Liang, Yueyong Xiao
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Advanced Science
Subjects:
chemotherapy
DNA damage
heat shock protein
mild‐photothermal therapy
mitoxantrone
polymeric micelle
Online Access:https://doi.org/10.1002/advs.202206707

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