System inflammation role in cardiovascular and obstetric pathology

Recently, the role of inflammatory component in cardiovascular disease (CVD) pathogenesis has been widely accepted, and traditional CVD risk factors (RFs) were supplemented by the evidence on pro-inflammatory mediators’ role in atherosclerosis pathogenesis. At the same time, there is an overlap betw...

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Main Authors: M. B. Igitova, E. V. Wobieva, E. V. Osipova, N. P. Gol’tsova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2009-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1165
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author M. B. Igitova
E. V. Wobieva
E. V. Osipova
N. P. Gol’tsova
author_facet M. B. Igitova
E. V. Wobieva
E. V. Osipova
N. P. Gol’tsova
author_sort M. B. Igitova
collection DOAJ
description Recently, the role of inflammatory component in cardiovascular disease (CVD) pathogenesis has been widely accepted, and traditional CVD risk factors (RFs) were supplemented by the evidence on pro-inflammatory mediators’ role in atherosclerosis pathogenesis. At the same time, there is an overlap between chnical RFs of atherosclerosis and typical obstetric complications — gestoses and chronic placental insufficiency. Highly informative predictor of atherosclerotic complications is a marker of intravascular inflammation — highly sensitive C-reactive protein (hsCRP). The studies on hsCRP in obstetric complications are scarce and contradictory, and at the moment, there is no clear hypothesis of systemic inflammation role in pregnancy physiology and pathology.
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spelling doaj.art-481e7e1329054ffcaa53b6d4b43d79dd2023-03-13T07:23:16Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252009-02-01818187877System inflammation role in cardiovascular and obstetric pathologyM. B. Igitova0E. V. Wobieva1E. V. Osipova2N. P. Gol’tsova3ГОУ ВПО Алтайский государственный медицинский университет РосздраваГОУ ВПО Алтайский государственный медицинский университет РосздраваГОУ ВПО Алтайский государственный медицинский университет РосздраваГОУ ВПО Алтайский государственный медицинский университет РосздраваRecently, the role of inflammatory component in cardiovascular disease (CVD) pathogenesis has been widely accepted, and traditional CVD risk factors (RFs) were supplemented by the evidence on pro-inflammatory mediators’ role in atherosclerosis pathogenesis. At the same time, there is an overlap between chnical RFs of atherosclerosis and typical obstetric complications — gestoses and chronic placental insufficiency. Highly informative predictor of atherosclerotic complications is a marker of intravascular inflammation — highly sensitive C-reactive protein (hsCRP). The studies on hsCRP in obstetric complications are scarce and contradictory, and at the moment, there is no clear hypothesis of systemic inflammation role in pregnancy physiology and pathology.https://cardiovascular.elpub.ru/jour/article/view/1165с-реактивный белоквоспалениеатеросклерозбеременностьакушерские осложнения
spellingShingle M. B. Igitova
E. V. Wobieva
E. V. Osipova
N. P. Gol’tsova
System inflammation role in cardiovascular and obstetric pathology
Кардиоваскулярная терапия и профилактика
с-реактивный белок
воспаление
атеросклероз
беременность
акушерские осложнения
title System inflammation role in cardiovascular and obstetric pathology
title_full System inflammation role in cardiovascular and obstetric pathology
title_fullStr System inflammation role in cardiovascular and obstetric pathology
title_full_unstemmed System inflammation role in cardiovascular and obstetric pathology
title_short System inflammation role in cardiovascular and obstetric pathology
title_sort system inflammation role in cardiovascular and obstetric pathology
topic с-реактивный белок
воспаление
атеросклероз
беременность
акушерские осложнения
url https://cardiovascular.elpub.ru/jour/article/view/1165
work_keys_str_mv AT mbigitova systeminflammationroleincardiovascularandobstetricpathology
AT evwobieva systeminflammationroleincardiovascularandobstetricpathology
AT evosipova systeminflammationroleincardiovascularandobstetricpathology
AT npgoltsova systeminflammationroleincardiovascularandobstetricpathology