Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration

Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration

Abstract Background Efficient and stable delivery of neurotrophic factors (NTFs) is crucial to provide suitable microenvironment for peripheral nerve regeneration. Neurotrophin-3 (NT-3) is an important NTF during peripheral nerve regeneration which is scarce in the first few weeks of nerve defect. E...

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Bibliographic Details
Main Authors: Zheng Yang, Yang Yang, Yichi Xu, Weiqian Jiang, Yan Shao, Jiahua Xing, Youbai Chen, Yan Han
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Stem Cell Research & Therapy
Subjects:
Peripheral nerve
Regeneration
Exosomes
Neurotrophin-3
Nerve guidance conduit
Online Access:https://doi.org/10.1186/s13287-021-02528-x

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