Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound Encapsulation
In recent years, starch nanoparticles (SNPs) have attracted growing attention due to their unique properties as a sustainable alternative to common nanomaterials since they are natural, renewable and biodegradable. SNPs can be obtained by the breakdown of starch granules through different techniques...
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MDPI AG
2021-05-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/10/4547 |
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| author | Diana Morán Gemma Gutiérrez María Carmen Blanco-López Ali Marefati Marilyn Rayner María Matos |
| author_facet | Diana Morán Gemma Gutiérrez María Carmen Blanco-López Ali Marefati Marilyn Rayner María Matos |
| author_sort | Diana Morán |
| collection | DOAJ |
| description | In recent years, starch nanoparticles (SNPs) have attracted growing attention due to their unique properties as a sustainable alternative to common nanomaterials since they are natural, renewable and biodegradable. SNPs can be obtained by the breakdown of starch granules through different techniques which include both physical and chemical methods. The final properties of the SNPs are strongly influenced by the synthesis method used as well as the operational conditions, where a controlled and monodispersed size is crucial for certain bioapplications. SNPs are considered to be a good vehicle to improve the controlled release of many bioactive compounds in different research fields due to their high biocompatibility, potential functionalization, and high surface/volume ratio. Their applications are frequently found in medicine, cosmetics, biotechnology, or the food industry, among others. Both the encapsulation properties as well as the releasing processes of the bioactive compounds are highly influenced by the size of the SNPs. In this review, a general description of the different types of SNPs (whole and hollow) synthesis methods is provided as well as on different techniques for encapsulating bioactive compounds, including direct and indirect methods, with application in several fields. Starches from different botanical sources and different bioactive compounds are compared with respect to the efficacy in vitro and in vivo. Applications and future research trends on SNPs synthesis have been included and discussed. |
| first_indexed | 2024-03-10T11:20:54Z |
| format | Article |
| id | doaj.art-481f788f83a8454b88ba83f507b081ef |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T11:20:54Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-481f788f83a8454b88ba83f507b081ef2023-11-21T20:00:40ZengMDPI AGApplied Sciences2076-34172021-05-011110454710.3390/app11104547Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound EncapsulationDiana Morán0Gemma Gutiérrez1María Carmen Blanco-López2Ali Marefati3Marilyn Rayner4María Matos5Department of Chemical and Environmental Engineering, University of Oviedo, Julián Clavería 8, 33006 Oviedo, SpainDepartment of Chemical and Environmental Engineering, University of Oviedo, Julián Clavería 8, 33006 Oviedo, SpainInstituto Universitario de Biotecnología de Asturias, University of Oviedo, 33006 Oviedo, SpainDepartment of Food Technology, Engineering, and Nutrition, Lund University, P.O. Box 124, SE 221 00 Lund, SwedenDepartment of Food Technology, Engineering, and Nutrition, Lund University, P.O. Box 124, SE 221 00 Lund, SwedenDepartment of Chemical and Environmental Engineering, University of Oviedo, Julián Clavería 8, 33006 Oviedo, SpainIn recent years, starch nanoparticles (SNPs) have attracted growing attention due to their unique properties as a sustainable alternative to common nanomaterials since they are natural, renewable and biodegradable. SNPs can be obtained by the breakdown of starch granules through different techniques which include both physical and chemical methods. The final properties of the SNPs are strongly influenced by the synthesis method used as well as the operational conditions, where a controlled and monodispersed size is crucial for certain bioapplications. SNPs are considered to be a good vehicle to improve the controlled release of many bioactive compounds in different research fields due to their high biocompatibility, potential functionalization, and high surface/volume ratio. Their applications are frequently found in medicine, cosmetics, biotechnology, or the food industry, among others. Both the encapsulation properties as well as the releasing processes of the bioactive compounds are highly influenced by the size of the SNPs. In this review, a general description of the different types of SNPs (whole and hollow) synthesis methods is provided as well as on different techniques for encapsulating bioactive compounds, including direct and indirect methods, with application in several fields. Starches from different botanical sources and different bioactive compounds are compared with respect to the efficacy in vitro and in vivo. Applications and future research trends on SNPs synthesis have been included and discussed.https://www.mdpi.com/2076-3417/11/10/4547starch nanoparticles (SNPs)SNPs synthesisbioactive compoundsdrug deliveryencapsulation efficiency |
| spellingShingle | Diana Morán Gemma Gutiérrez María Carmen Blanco-López Ali Marefati Marilyn Rayner María Matos Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound Encapsulation Applied Sciences starch nanoparticles (SNPs) SNPs synthesis bioactive compounds drug delivery encapsulation efficiency |
| title | Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound Encapsulation |
| title_full | Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound Encapsulation |
| title_fullStr | Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound Encapsulation |
| title_full_unstemmed | Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound Encapsulation |
| title_short | Synthesis of Starch Nanoparticles and Their Applications for Bioactive Compound Encapsulation |
| title_sort | synthesis of starch nanoparticles and their applications for bioactive compound encapsulation |
| topic | starch nanoparticles (SNPs) SNPs synthesis bioactive compounds drug delivery encapsulation efficiency |
| url | https://www.mdpi.com/2076-3417/11/10/4547 |
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