Diverse Profiles of Ricin-Cell Interactions in the Lung Following Intranasal Exposure to Ricin

Diverse Profiles of Ricin-Cell Interactions in the Lung Following Intranasal Exposure to Ricin

Ricin, a plant-derived exotoxin, inhibits protein synthesis by ribosomal inactivation. Due to its wide availability and ease of preparation, ricin is considered a biothreat, foremost by respiratory exposure. We examined the in vivo interactions between ricin and cells of the lungs in mice intranasal...

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Bibliographic Details
Main Authors: Anita Sapoznikov, Reut Falach, Ohad Mazor, Ron Alcalay, Yoav Gal, Nehama Seliger, Tamar Sabo, Chanoch Kronman
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Toxins
Subjects:
ricin
lung
binding
macrophages
epithelial cells
alveolar type II cells
Online Access:http://www.mdpi.com/2072-6651/7/11/4817

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