Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort study

Abstract Background Perinatal depression is a significant contributor to maternal morbidity and mortality globally. Migrant women, particularly those living in low- and middle-income settings, represent a particularly vulnerable group due to stressors experienced before, during and after migration....

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Main Authors: Gracia Fellmeth, Emma Plugge, Mina Fazel, May May Oo, Mupawjay Pimanpanarak, Yuwapha Phichitpadungtham, Kerry Wai, Prakaykaew Charunwatthana, Julie A. Simpson, François Nosten, Raymond Fitzpatrick, Rose McGready
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Language:English
Published: BMC 2020-04-01
Series:BMC Psychiatry
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Online Access:http://link.springer.com/article/10.1186/s12888-020-02572-6
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author Gracia Fellmeth
Emma Plugge
Mina Fazel
May May Oo
Mupawjay Pimanpanarak
Yuwapha Phichitpadungtham
Kerry Wai
Prakaykaew Charunwatthana
Julie A. Simpson
François Nosten
Raymond Fitzpatrick
Rose McGready
author_facet Gracia Fellmeth
Emma Plugge
Mina Fazel
May May Oo
Mupawjay Pimanpanarak
Yuwapha Phichitpadungtham
Kerry Wai
Prakaykaew Charunwatthana
Julie A. Simpson
François Nosten
Raymond Fitzpatrick
Rose McGready
author_sort Gracia Fellmeth
collection DOAJ
description Abstract Background Perinatal depression is a significant contributor to maternal morbidity and mortality globally. Migrant women, particularly those living in low- and middle-income settings, represent a particularly vulnerable group due to stressors experienced before, during and after migration. The vast majority of global migration flows occurring within and between low- and middle-income regions, yet existing evidence focuses predominantly on migrants in high-income destinations. This study aimed to redress this significant gap in the evidence by determining the prevalence and determinants of perinatal depression among migrant women on the Thai-Myanmar border. Methods A cohort of labour migrant and refugee women was followed-up from the first trimester of pregnancy to one month post-partum. Depression status was assessed in the first, second and third trimesters of pregnancy and at one month post-partum using the Structured Clinical Interview for the Diagnosis of DSM-IV Disorders. Women diagnosed with depression had immediate access to care. Data on potential demographic, social and clinical associated factors was collected using a questionnaire. Prevalence and incidence of any depressive disorder and moderate-severe depressive disorder was calculated. Univariable and multivariable logistic regression using complete case analysis was used to estimate odds ratios (OR) of association between exposure variables and depression status. Results Five hundred sixty-eight women participated. Period prevalence (from first trimester of pregnancy to one month post-partum) of moderate-severe perinatal depression was 18.5% (95% CI 15.4–21.9%). Overall, 15.4% (95% CI 11.8–19.6%) of women developed new-onset moderate-severe depression during the study period. Forty-two participants received treatment for depression. Risk factors were interpersonal violence (OR 4.5; 95% CI 1.9–11.1); history of trauma (OR 2.4; 95% CI 1.4–4.3); self-reported history of depression (OR 2.3; 95% CI 1.2–4.2); labour migrant status (OR 2.1; 95% CI 1.1–4.0); low social support (OR 2.1; 95% CI 1.1–3.7); and maternal age (OR 1.1 per year; 95% CI 1.0–1.1). Limitations of the study include that culturally specific manifestations of depression may have been missed. Conclusions Perinatal depression represents a significant burden among migrant women on the Thai-Myanmar border. Programmes to address the determinants along with early case identification and effective treatment and referral systems are key to addressing perinatal depression in this low-resource setting.
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spelling doaj.art-4829063b9fe04195999532b224fe894c2022-12-22T02:04:49ZengBMCBMC Psychiatry1471-244X2020-04-0120111410.1186/s12888-020-02572-6Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort studyGracia Fellmeth0Emma Plugge1Mina Fazel2May May Oo3Mupawjay Pimanpanarak4Yuwapha Phichitpadungtham5Kerry Wai6Prakaykaew Charunwatthana7Julie A. Simpson8François Nosten9Raymond Fitzpatrick10Rose McGready11Nuffield Department of Population Health, University of OxfordHealth and Justice Team, Health Improvement Directorate, Public Health EnglandDepartment of Psychiatry, University of Oxford, Warneford HospitalShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol UniversityShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol UniversityShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol UniversityShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol UniversityFaculty of Tropical Medicine, Mahidol UniversityCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of MelbourneShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol UniversityNuffield Department of Population Health, University of OxfordShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol UniversityAbstract Background Perinatal depression is a significant contributor to maternal morbidity and mortality globally. Migrant women, particularly those living in low- and middle-income settings, represent a particularly vulnerable group due to stressors experienced before, during and after migration. The vast majority of global migration flows occurring within and between low- and middle-income regions, yet existing evidence focuses predominantly on migrants in high-income destinations. This study aimed to redress this significant gap in the evidence by determining the prevalence and determinants of perinatal depression among migrant women on the Thai-Myanmar border. Methods A cohort of labour migrant and refugee women was followed-up from the first trimester of pregnancy to one month post-partum. Depression status was assessed in the first, second and third trimesters of pregnancy and at one month post-partum using the Structured Clinical Interview for the Diagnosis of DSM-IV Disorders. Women diagnosed with depression had immediate access to care. Data on potential demographic, social and clinical associated factors was collected using a questionnaire. Prevalence and incidence of any depressive disorder and moderate-severe depressive disorder was calculated. Univariable and multivariable logistic regression using complete case analysis was used to estimate odds ratios (OR) of association between exposure variables and depression status. Results Five hundred sixty-eight women participated. Period prevalence (from first trimester of pregnancy to one month post-partum) of moderate-severe perinatal depression was 18.5% (95% CI 15.4–21.9%). Overall, 15.4% (95% CI 11.8–19.6%) of women developed new-onset moderate-severe depression during the study period. Forty-two participants received treatment for depression. Risk factors were interpersonal violence (OR 4.5; 95% CI 1.9–11.1); history of trauma (OR 2.4; 95% CI 1.4–4.3); self-reported history of depression (OR 2.3; 95% CI 1.2–4.2); labour migrant status (OR 2.1; 95% CI 1.1–4.0); low social support (OR 2.1; 95% CI 1.1–3.7); and maternal age (OR 1.1 per year; 95% CI 1.0–1.1). Limitations of the study include that culturally specific manifestations of depression may have been missed. Conclusions Perinatal depression represents a significant burden among migrant women on the Thai-Myanmar border. Programmes to address the determinants along with early case identification and effective treatment and referral systems are key to addressing perinatal depression in this low-resource setting.http://link.springer.com/article/10.1186/s12888-020-02572-6PerinatalDepressionMigrantRefugeeLow- and middle-income
spellingShingle Gracia Fellmeth
Emma Plugge
Mina Fazel
May May Oo
Mupawjay Pimanpanarak
Yuwapha Phichitpadungtham
Kerry Wai
Prakaykaew Charunwatthana
Julie A. Simpson
François Nosten
Raymond Fitzpatrick
Rose McGready
Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort study
BMC Psychiatry
Perinatal
Depression
Migrant
Refugee
Low- and middle-income
title Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort study
title_full Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort study
title_fullStr Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort study
title_full_unstemmed Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort study
title_short Prevalence and determinants of perinatal depression among labour migrant and refugee women on the Thai-Myanmar border: a cohort study
title_sort prevalence and determinants of perinatal depression among labour migrant and refugee women on the thai myanmar border a cohort study
topic Perinatal
Depression
Migrant
Refugee
Low- and middle-income
url http://link.springer.com/article/10.1186/s12888-020-02572-6
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