Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways

Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways

RationaleFood allergy is a prevalent disease in the U.S., affecting nearly 30 million people. The primary management strategy for this condition is food avoidance, as limited treatment options are available. The elevation of pathologic IgE and over-reactive mast cells/basophils is a central factor i...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Ibrahim Musa, Zhen-Zhen Wang, Nan Yang, Xiu-Min Li
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	Frontiers Media S.A. 2024-08-01
Cyfres:	Frontiers in Immunology
Pynciau:	formononetin food anaphylaxis computational modeling target mining molecular docking gene ontology enrichment
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427563/full

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