Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways

Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways

RationaleFood allergy is a prevalent disease in the U.S., affecting nearly 30 million people. The primary management strategy for this condition is food avoidance, as limited treatment options are available. The elevation of pathologic IgE and over-reactive mast cells/basophils is a central factor i...

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Bibliografiska uppgifter
Huvudupphovsmän: Ibrahim Musa, Zhen-Zhen Wang, Nan Yang, Xiu-Min Li
Materialtyp: Artikel
Språk:English
Publicerad: Frontiers Media S.A. 2024-08-01
Serie:Frontiers in Immunology
Ämnen:
formononetin
food anaphylaxis
computational modeling
target mining
molecular docking
gene ontology enrichment
Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427563/full

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