Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways

RationaleFood allergy is a prevalent disease in the U.S., affecting nearly 30 million people. The primary management strategy for this condition is food avoidance, as limited treatment options are available. The elevation of pathologic IgE and over-reactive mast cells/basophils is a central factor i...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ibrahim Musa, Zhen-Zhen Wang, Nan Yang, Xiu-Min Li
Format: Artikel
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2024-08-01
Schriftenreihe:Frontiers in Immunology
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Online Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427563/full