Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways

RationaleFood allergy is a prevalent disease in the U.S., affecting nearly 30 million people. The primary management strategy for this condition is food avoidance, as limited treatment options are available. The elevation of pathologic IgE and over-reactive mast cells/basophils is a central factor i...

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Main Authors: Ibrahim Musa, Zhen-Zhen Wang, Nan Yang, Xiu-Min Li
פורמט: Article
שפה:English
יצא לאור: Frontiers Media S.A. 2024-08-01
סדרה:Frontiers in Immunology
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גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427563/full