Formononetin inhibits IgE by huPlasma/PBMCs and mast cells/basophil activation via JAK/STAT/PI3-Akt pathways

RationaleFood allergy is a prevalent disease in the U.S., affecting nearly 30 million people. The primary management strategy for this condition is food avoidance, as limited treatment options are available. The elevation of pathologic IgE and over-reactive mast cells/basophils is a central factor i...

Полное описание

Библиографические подробности
Главные авторы: Ibrahim Musa, Zhen-Zhen Wang, Nan Yang, Xiu-Min Li
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2024-08-01
Серии:Frontiers in Immunology
Предметы:
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427563/full