Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires
SARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the natural infection of two cats by SARS-CoV-2, in Argentina, whose owner had been...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Veterinary Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2022.790058/full |
| _version_ | 1819125455429566464 |
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| author | Andrea Pecora Dario Amilcar Malacari Marina Valeria Mozgovoj Marina Valeria Mozgovoj María de los Ángeles Díaz Andrea Verónica Peralta Marco Cacciabue Andrea Fabiana Puebla Cristian Carusso Silvia Leonor Mundo María Mora Gonzalez Lopez Ledesma Andrea Vanesa Gamarnik Osvaldo Rinaldi Osvaldo Vidal Javier Mas Javier Mas María José Dus Santos María José Dus Santos |
| author_facet | Andrea Pecora Dario Amilcar Malacari Marina Valeria Mozgovoj Marina Valeria Mozgovoj María de los Ángeles Díaz Andrea Verónica Peralta Marco Cacciabue Andrea Fabiana Puebla Cristian Carusso Silvia Leonor Mundo María Mora Gonzalez Lopez Ledesma Andrea Vanesa Gamarnik Osvaldo Rinaldi Osvaldo Vidal Javier Mas Javier Mas María José Dus Santos María José Dus Santos |
| author_sort | Andrea Pecora |
| collection | DOAJ |
| description | SARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the natural infection of two cats by SARS-CoV-2, in Argentina, whose owner had been previously infected by SARS-CoV-2. Viral genetic material was detected in feline oropharyngeal (OP) and rectal (R) swab by RT-qPCR, and sequence analysis revealed that the virus infecting the owner and one cat were genetically similar. The alpha variant (B.1.1.7 lineage) was identified with a unique additional mutation, strongly suggesting human-to-cat route of transmission. This study reinforces the One Health concept and the importance of integrating human, animal, and environmental perspectives to promptly address relevant health issues. |
| first_indexed | 2024-12-22T07:40:25Z |
| format | Article |
| id | doaj.art-4829786d9d5c4aad95ccb1b9f472b5d5 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-22T07:40:25Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-4829786d9d5c4aad95ccb1b9f472b5d52022-12-21T18:33:46ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692022-03-01910.3389/fvets.2022.790058790058Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos AiresAndrea Pecora0Dario Amilcar Malacari1Marina Valeria Mozgovoj2Marina Valeria Mozgovoj3María de los Ángeles Díaz4Andrea Verónica Peralta5Marco Cacciabue6Andrea Fabiana Puebla7Cristian Carusso8Silvia Leonor Mundo9María Mora Gonzalez Lopez Ledesma10Andrea Vanesa Gamarnik11Osvaldo Rinaldi12Osvaldo Vidal13Javier Mas14Javier Mas15María José Dus Santos16María José Dus Santos17Centro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto de Virología e Innovaciones Tecnológicas, Instituto Nacional de Tecnología Agropecuaria (INTA)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, ArgentinaDiagnogen S.A., Buenos Aires, ArgentinaInstituto de Biotecnología, Universidad Nacional de Hurlingham, Buenos Aires, ArgentinaCentro de Agroindustria, Instituto de Ciencia y Tecnología de Sistemas Alimentarios Sustentables, Instituto Nacional de Tecnología Agropecuaria (INTA)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, ArgentinaSecretaria de Salud de la Municipalidad de la Matanza, Ministerio de Salud, Buenos Aires, ArgentinaCentro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto de Agrobiotecnología y Biología Molecular, Instituto Nacional de Tecnología Agropecuaria (INTA)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, ArgentinaCentro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto de Agrobiotecnología y Biología Molecular, Instituto Nacional de Tecnología Agropecuaria (INTA)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, ArgentinaCentro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto de Agrobiotecnología y Biología Molecular, Instituto Nacional de Tecnología Agropecuaria (INTA)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, ArgentinaFacultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires, ArgentinaFacultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires, ArgentinaInstituto de Investigaciones Bioquímicas de Buenos Aires (IIBBA, CONICET-Fundación Instituto Leloir), Buenos Aires, ArgentinaInstituto de Investigaciones Bioquímicas de Buenos Aires (IIBBA, CONICET-Fundación Instituto Leloir), Buenos Aires, ArgentinaVeterinaria Rinaldi Vidal, Buenos Aires, ArgentinaVeterinaria Rinaldi Vidal, Buenos Aires, ArgentinaDiagnogen S.A., Buenos Aires, Argentina0Diagnotest SRL, Buenos Aires, ArgentinaCentro de Investigaciones en Ciencias Veterinarias y Agronómicas, Instituto de Virología e Innovaciones Tecnológicas, Instituto Nacional de Tecnología Agropecuaria (INTA)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, ArgentinaInstituto de Biotecnología, Universidad Nacional de Hurlingham, Buenos Aires, ArgentinaSARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the natural infection of two cats by SARS-CoV-2, in Argentina, whose owner had been previously infected by SARS-CoV-2. Viral genetic material was detected in feline oropharyngeal (OP) and rectal (R) swab by RT-qPCR, and sequence analysis revealed that the virus infecting the owner and one cat were genetically similar. The alpha variant (B.1.1.7 lineage) was identified with a unique additional mutation, strongly suggesting human-to-cat route of transmission. This study reinforces the One Health concept and the importance of integrating human, animal, and environmental perspectives to promptly address relevant health issues.https://www.frontiersin.org/articles/10.3389/fvets.2022.790058/fullSARS-CoV-2COVID-19reverse zoonosiscatsOne Health |
| spellingShingle | Andrea Pecora Dario Amilcar Malacari Marina Valeria Mozgovoj Marina Valeria Mozgovoj María de los Ángeles Díaz Andrea Verónica Peralta Marco Cacciabue Andrea Fabiana Puebla Cristian Carusso Silvia Leonor Mundo María Mora Gonzalez Lopez Ledesma Andrea Vanesa Gamarnik Osvaldo Rinaldi Osvaldo Vidal Javier Mas Javier Mas María José Dus Santos María José Dus Santos Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires Frontiers in Veterinary Science SARS-CoV-2 COVID-19 reverse zoonosis cats One Health |
| title | Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires |
| title_full | Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires |
| title_fullStr | Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires |
| title_full_unstemmed | Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires |
| title_short | Anthropogenic Infection of Domestic Cats With SARS-CoV-2 Alpha Variant B.1.1.7 Lineage in Buenos Aires |
| title_sort | anthropogenic infection of domestic cats with sars cov 2 alpha variant b 1 1 7 lineage in buenos aires |
| topic | SARS-CoV-2 COVID-19 reverse zoonosis cats One Health |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2022.790058/full |
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