Childhood polyarteritis nodosa: A rare presentation
Polyarteritis nodosa (PAN) is a rare systemic vasculitis characterized by necrotizing arteritis of small to medium-sized arteries. It manifests as skin ulceration, hypertension, abdominal pain, digital gangrene, subcutaneous nodules etc. Childhood polyarteritis nodosa (CPAN) is a rare and often fata...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Manipal College of Medical Sciences, Pokhara
2016-10-01
|
| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/15724 |
| _version_ | 1824004142621786112 |
|---|---|
| author | Sandeep Lahiry |
| author_facet | Sandeep Lahiry |
| author_sort | Sandeep Lahiry |
| collection | DOAJ |
| description | Polyarteritis nodosa (PAN) is a rare systemic vasculitis characterized by necrotizing arteritis of small to medium-sized arteries. It manifests as skin ulceration, hypertension, abdominal pain, digital gangrene, subcutaneous nodules etc. Childhood polyarteritis nodosa (CPAN) is a rare and often fatal disease. Clinically, CPAN often is part of the spectrum of Kawasaki disease (KD). There is no specific serological marker for diagnosis and confirmation is based on histopathology. Most common mode of pharmacological therapy includes corticosteroid or cyclophosphamide, along with antimicrobials for secondary infection prevention and plasmapheresis.
Here, we present a case of a 16year old boy with multiple skin ulceration, digital gangrene with few non-specific signs and symptoms, diagnosed as a case of PAN, underwent regular therapy and follow-up. |
| first_indexed | 2024-12-18T19:49:41Z |
| format | Article |
| id | doaj.art-4829f72464194b279b0129140d519773 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-12-18T19:49:41Z |
| publishDate | 2016-10-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-4829f72464194b279b0129140d5197732022-12-21T20:55:13ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762016-10-01769496https://doi.org/10.3126/ajms.v7i6.15724Childhood polyarteritis nodosa: A rare presentationSandeep Lahiry 0MBBS; Post Graduate Trainee Department of Pharmacology Institute of Post Graduate Medical Education and Research, Kolkata http://orcid.org/0000-0002-6919-0530Polyarteritis nodosa (PAN) is a rare systemic vasculitis characterized by necrotizing arteritis of small to medium-sized arteries. It manifests as skin ulceration, hypertension, abdominal pain, digital gangrene, subcutaneous nodules etc. Childhood polyarteritis nodosa (CPAN) is a rare and often fatal disease. Clinically, CPAN often is part of the spectrum of Kawasaki disease (KD). There is no specific serological marker for diagnosis and confirmation is based on histopathology. Most common mode of pharmacological therapy includes corticosteroid or cyclophosphamide, along with antimicrobials for secondary infection prevention and plasmapheresis. Here, we present a case of a 16year old boy with multiple skin ulceration, digital gangrene with few non-specific signs and symptoms, diagnosed as a case of PAN, underwent regular therapy and follow-up.https://www.nepjol.info/index.php/AJMS/article/view/15724childhood polyarteritis nodosacorticosteroidsmycophenolate mofetil |
| spellingShingle | Sandeep Lahiry Childhood polyarteritis nodosa: A rare presentation Asian Journal of Medical Sciences childhood polyarteritis nodosa corticosteroids mycophenolate mofetil |
| title | Childhood polyarteritis nodosa: A rare presentation |
| title_full | Childhood polyarteritis nodosa: A rare presentation |
| title_fullStr | Childhood polyarteritis nodosa: A rare presentation |
| title_full_unstemmed | Childhood polyarteritis nodosa: A rare presentation |
| title_short | Childhood polyarteritis nodosa: A rare presentation |
| title_sort | childhood polyarteritis nodosa a rare presentation |
| topic | childhood polyarteritis nodosa corticosteroids mycophenolate mofetil |
| url | https://www.nepjol.info/index.php/AJMS/article/view/15724 |
| work_keys_str_mv | AT sandeeplahiry childhoodpolyarteritisnodosaararepresentation |