Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review
Purpose: To report changing trends in indications and techniques of corneal transplantation in Iran. Methods: We reviewed eye bank records of 47,129 patients who had undergone corneal transplantation between 2006 and 2013 at different eye centers throughout Iran. Results: The most common indication...
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| Format: | Article |
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Knowledge E
2016-01-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=2;spage=146;epage=152;aulast=Rezaei |
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| author | Mozhgan Rezaei Kanavi Mohammad Ali Javadi Tahmineh Motevasseli Tahereh Chamani Mahnoush Rezaei Kanavi Bahareh Kheiri Sare Safi |
| author_facet | Mozhgan Rezaei Kanavi Mohammad Ali Javadi Tahmineh Motevasseli Tahereh Chamani Mahnoush Rezaei Kanavi Bahareh Kheiri Sare Safi |
| author_sort | Mozhgan Rezaei Kanavi |
| collection | DOAJ |
| description | Purpose: To report changing trends in indications and techniques of corneal transplantation in Iran.
Methods: We reviewed eye bank records of 47,129 patients who had undergone corneal transplantation between 2006 and 2013 at different eye centers throughout Iran.
Results: The most common indication for corneal transplantation was keratoconus (KCN, n = 21,350 eyes, 45.3%), followed by bullous keratopathy (BK, n = 8,566 eyes, 18.2%), corneal opacity and scar (COS, n = 7,158 eyes, 15.2%), graft failure (n = 3,252 eyes, 6.9%), corneal dystrophies (n = 2,553 eyes, 5.4%), and infectious keratitis (n = 2,238 eyes, 4.7%). Over the study period, there was a significant increase in the frequency of BK (P = 0.001) and graft failure (P = 0.025), and a significant decrease in the relative frequency of COS (P = 0.012). The prevalence of KCN (P = 0.172), infectious keratitis (P = 0.107), and corneal dystrophies (P = 0.836) remained unchanged. The most common technique of corneal transplantation was penetrating keratoplasty (PKP, n = 33,476 eyes, 71.0%), followed by deep anterior lamellar keratoplasty (DALK, n = 8,363 eyes, 17.7%), Descemet's stripping automated endothelial keratoplasty (DSAEK, n = 3,516 eyes, 7.5%), tectonic (n = 1752, 3.7%), and keratolimbal allograft (KLAL, n = 19 eyes, 0.1%). Regarding the shift in surgical techniques, a significant increase was observed in DSAEK (P < 0.001), whereas PKP was significantly decreased (P = 0.005) over the 8-year period. No significant change was seen in the rates of DALK (P = 0.354), tectonic graft (P < 0.999) and KLAL (P = 0.151).
Conclusion: KCN was the most common indication and PKP was the most prevalent technique used for corneal transplantation. Significant changes in surgical techniques were observed over the past 8 years; DSAEK demonstrated an increasing trend while PKP showed a decrease. |
| first_indexed | 2024-04-12T15:41:55Z |
| format | Article |
| id | doaj.art-482ed1bc6c9c41548921ab3ac9f552f2 |
| institution | Directory Open Access Journal |
| issn | 2008-322X |
| language | English |
| last_indexed | 2024-04-12T15:41:55Z |
| publishDate | 2016-01-01 |
| publisher | Knowledge E |
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| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-482ed1bc6c9c41548921ab3ac9f552f22022-12-22T03:26:45ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2016-01-0111214615210.4103/2008-322X.183930Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year reviewMozhgan Rezaei KanaviMohammad Ali JavadiTahmineh MotevasseliTahereh ChamaniMahnoush Rezaei KanaviBahareh KheiriSare SafiPurpose: To report changing trends in indications and techniques of corneal transplantation in Iran. Methods: We reviewed eye bank records of 47,129 patients who had undergone corneal transplantation between 2006 and 2013 at different eye centers throughout Iran. Results: The most common indication for corneal transplantation was keratoconus (KCN, n = 21,350 eyes, 45.3%), followed by bullous keratopathy (BK, n = 8,566 eyes, 18.2%), corneal opacity and scar (COS, n = 7,158 eyes, 15.2%), graft failure (n = 3,252 eyes, 6.9%), corneal dystrophies (n = 2,553 eyes, 5.4%), and infectious keratitis (n = 2,238 eyes, 4.7%). Over the study period, there was a significant increase in the frequency of BK (P = 0.001) and graft failure (P = 0.025), and a significant decrease in the relative frequency of COS (P = 0.012). The prevalence of KCN (P = 0.172), infectious keratitis (P = 0.107), and corneal dystrophies (P = 0.836) remained unchanged. The most common technique of corneal transplantation was penetrating keratoplasty (PKP, n = 33,476 eyes, 71.0%), followed by deep anterior lamellar keratoplasty (DALK, n = 8,363 eyes, 17.7%), Descemet's stripping automated endothelial keratoplasty (DSAEK, n = 3,516 eyes, 7.5%), tectonic (n = 1752, 3.7%), and keratolimbal allograft (KLAL, n = 19 eyes, 0.1%). Regarding the shift in surgical techniques, a significant increase was observed in DSAEK (P < 0.001), whereas PKP was significantly decreased (P = 0.005) over the 8-year period. No significant change was seen in the rates of DALK (P = 0.354), tectonic graft (P < 0.999) and KLAL (P = 0.151). Conclusion: KCN was the most common indication and PKP was the most prevalent technique used for corneal transplantation. Significant changes in surgical techniques were observed over the past 8 years; DSAEK demonstrated an increasing trend while PKP showed a decrease.http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=2;spage=146;epage=152;aulast=RezaeiCorneal Transplantation; Keratoconus; Surgical Technique; Trends |
| spellingShingle | Mozhgan Rezaei Kanavi Mohammad Ali Javadi Tahmineh Motevasseli Tahereh Chamani Mahnoush Rezaei Kanavi Bahareh Kheiri Sare Safi Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review Journal of Ophthalmic & Vision Research Corneal Transplantation; Keratoconus; Surgical Technique; Trends |
| title | Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review |
| title_full | Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review |
| title_fullStr | Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review |
| title_full_unstemmed | Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review |
| title_short | Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review |
| title_sort | trends in indications and techniques of corneal transplantation in iran from 2006 to 2013 an 8 year review |
| topic | Corneal Transplantation; Keratoconus; Surgical Technique; Trends |
| url | http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=2;spage=146;epage=152;aulast=Rezaei |
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