Chain-Selective Isotopic Labeling of the Heterodimeric Type III Secretion Chaperone, Scc4:Scc1, Reveals the Total Structural Rearrangement of the <i>Chlamydia trachomatis</i> Bi-Functional Protein, Scc4

Chain-Selective Isotopic Labeling of the Heterodimeric Type III Secretion Chaperone, Scc4:Scc1, Reveals the Total Structural Rearrangement of the <i>Chlamydia trachomatis</i> Bi-Functional Protein, Scc4

Scc4 is an unusual bi-functional protein from <i>Chlamydia trachomatis</i> (<i>CT</i>) that functions as a type III secretion system (T3SS) chaperone and an RNA polymerase (RNAP)-binding protein. Both functions require interactions with protein partners during specific stages...

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Bibliographic Details
Main Authors: Thilini O. Ukwaththage, Samantha M. Keane, Li Shen, Megan A. Macnaughtan
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomolecules
Subjects:
type III secretion
chaperone
transcription
<i>Chlamydia trachomatis</i>
NMR
Scc4
Online Access:https://www.mdpi.com/2218-273X/10/11/1480

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