The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms

Vascular spasm in patients with hemorrhage from rupture of cerebral aneurysms is the main cause of adverse outcomes of the disease. One way to treat persistent contraction of cerebral arteries is to use nimodipine and magnesium sulfate. This literature review presents studies on the use of nimodipin...

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Main Authors: Aleksandr A. Kalinkin, A. G. Vinokurov, O. N. Kalinkina, G. М. Yusubalieva, S. M. Chupalenkov
Format: Article
Language:English
Published: Eco-vector 2020-02-01
Series:Клиническая практика
Subjects:
Online Access:https://journals.eco-vector.com/clinpractice/article/viewFile/19137/pdf
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author Aleksandr A. Kalinkin
A. G. Vinokurov
O. N. Kalinkina
G. М. Yusubalieva
S. M. Chupalenkov
author_facet Aleksandr A. Kalinkin
A. G. Vinokurov
O. N. Kalinkina
G. М. Yusubalieva
S. M. Chupalenkov
author_sort Aleksandr A. Kalinkin
collection DOAJ
description Vascular spasm in patients with hemorrhage from rupture of cerebral aneurysms is the main cause of adverse outcomes of the disease. One way to treat persistent contraction of cerebral arteries is to use nimodipine and magnesium sulfate. This literature review presents studies on the use of nimodipine and magnesium sulfate in the treatment of vascular spasm, and highlights the main links of pathogenesis and drug action mechanisms.
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spelling doaj.art-48328a1774ea42299e840a936baace412023-09-02T06:48:05ZengEco-vectorКлиническая практика2220-30952618-86272020-02-01104536010.17816/clinpract1913716726The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysmsAleksandr A. Kalinkin0A. G. Vinokurov1O. N. Kalinkina2G. М. Yusubalieva3S. M. Chupalenkov4Federal Scientific and Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency of RussiaFederal Scientific and Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency of RussiaMoscow State University of Medicine and Dentistry a.n. A.I. EvdokimovFederal Scientific and Clinical Center of Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency of RussiaPirogov Russian National Research Medical UniversityVascular spasm in patients with hemorrhage from rupture of cerebral aneurysms is the main cause of adverse outcomes of the disease. One way to treat persistent contraction of cerebral arteries is to use nimodipine and magnesium sulfate. This literature review presents studies on the use of nimodipine and magnesium sulfate in the treatment of vascular spasm, and highlights the main links of pathogenesis and drug action mechanisms.https://journals.eco-vector.com/clinpractice/article/viewFile/19137/pdfaneurysmsubarachnoid hemorrhagevascular spasmcerebral ischemia
spellingShingle Aleksandr A. Kalinkin
A. G. Vinokurov
O. N. Kalinkina
G. М. Yusubalieva
S. M. Chupalenkov
The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms
Клиническая практика
aneurysm
subarachnoid hemorrhage
vascular spasm
cerebral ischemia
title The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms
title_full The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms
title_fullStr The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms
title_full_unstemmed The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms
title_short The role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms
title_sort role of nimodipine and magnesium sulfate in the prevention and treatment of vascular spasm in patients in the acute rupture of cerebral aneurysms
topic aneurysm
subarachnoid hemorrhage
vascular spasm
cerebral ischemia
url https://journals.eco-vector.com/clinpractice/article/viewFile/19137/pdf
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