Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysis

Abstract Background There is still a lack of remarkable consensus regarding the clinical efficacy of the application of fibular strut augmentation (FSA) combined with a locking plate for proximal humeral fractures. A systematic review and meta-analysis to assess the effect of the use of FSAs in open...

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Main Authors: Wei Nie, Zhaojun Wang, Fei Gu, Shizhuang Xu, Yang Yue, Anze Shao, Kefu Sun
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-022-03211-4
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author Wei Nie
Zhaojun Wang
Fei Gu
Shizhuang Xu
Yang Yue
Anze Shao
Kefu Sun
author_facet Wei Nie
Zhaojun Wang
Fei Gu
Shizhuang Xu
Yang Yue
Anze Shao
Kefu Sun
author_sort Wei Nie
collection DOAJ
description Abstract Background There is still a lack of remarkable consensus regarding the clinical efficacy of the application of fibular strut augmentation (FSA) combined with a locking plate for proximal humeral fractures. A systematic review and meta-analysis to assess the effect of the use of FSAs in open reduction and internal fixation of proximal humeral fractures was conducted. Methods A literature search was conducted in PubMed, Embase, Cochrane, Web of Science Core Collection, and ClinicalTrials.gov to identify trials that compared the clinical outcomes of proximal humeral fractures treated using a locking plate with or without FSA. The primary outcome measures were postoperative complications, radiographical findings, functional recovery scores, and postoperative range of motion (ROM). Data were pooled and analysed using a random-effects model based on the Der Simonian and Laird method. Results Eight studies involving 596 participants were included for further analysis. Compared with using a locking plate independently, the additional application of FSA was associated with the likelihood of lower risk of overall complications (OR 0.37; 95% CI 0.22–0.65; I 2  = 12.22%; 95% PI 0.14–0.98) and the rate of patients with orthopaedic complications (OR 0.48; 95% CI 0.25–0.92; I 2  = 7.52%; 95% PI 0.16–1.45), less changes in postoperative humeral head height (MD − 2.40; 95% CI − 2.49 to − 2.31; I 2  = 0.00%; 95% PI − 2.61 to − 2.20) and the neck–shaft angle (MD − 6.30; 95% CI − 7.23 to − 5.36; I 2  = 79.32%; 95% PI − 10.06 to − 2.53), superior functional outcomes (Constant–Murley score: MD 5.07; 95% CI 3.40 to 6.74; I 2  = 0.00%; 95% PI 2.361–7.78; American Shoulder and Elbow Surgeons Score: MD 5.08; 95% CI 3.67 to 6.49; I 2  = 0.00%; 95% PI 1.98–8.18), and better postoperative ROM in terms of forward elevation and external rotation. However, the evidence regarding postoperative abduction was insufficient. Conclusion Meta-analytic pooling of current evidence showed a significant association between the application of FSAs and favourable clinical outcomes in terms of postoperative complications, radiographical findings, functional recovery, and postoperative elevation and external rotation.
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spelling doaj.art-48365f36e29c416cb6b08cec70571b5e2022-12-22T04:02:06ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2022-06-0117111310.1186/s13018-022-03211-4Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysisWei Nie0Zhaojun Wang1Fei Gu2Shizhuang Xu3Yang Yue4Anze Shao5Kefu Sun6Department of Orthopedic Surgery, Lianyungang 2nd People’s HospitalDepartment of Orthopedic Surgery, Lianyungang 2nd People’s HospitalDepartment of Orthopedic Surgery, Lianyungang 2nd People’s HospitalDepartment of Orthopedic Surgery, Lianyungang 2nd People’s HospitalDepartment of Orthopedic Surgery, Lianyungang 2nd People’s HospitalDepartment of Orthopedic Surgery, Lianyungang 2nd People’s HospitalDepartment of Orthopedic Surgery, Lianyungang 2nd People’s HospitalAbstract Background There is still a lack of remarkable consensus regarding the clinical efficacy of the application of fibular strut augmentation (FSA) combined with a locking plate for proximal humeral fractures. A systematic review and meta-analysis to assess the effect of the use of FSAs in open reduction and internal fixation of proximal humeral fractures was conducted. Methods A literature search was conducted in PubMed, Embase, Cochrane, Web of Science Core Collection, and ClinicalTrials.gov to identify trials that compared the clinical outcomes of proximal humeral fractures treated using a locking plate with or without FSA. The primary outcome measures were postoperative complications, radiographical findings, functional recovery scores, and postoperative range of motion (ROM). Data were pooled and analysed using a random-effects model based on the Der Simonian and Laird method. Results Eight studies involving 596 participants were included for further analysis. Compared with using a locking plate independently, the additional application of FSA was associated with the likelihood of lower risk of overall complications (OR 0.37; 95% CI 0.22–0.65; I 2  = 12.22%; 95% PI 0.14–0.98) and the rate of patients with orthopaedic complications (OR 0.48; 95% CI 0.25–0.92; I 2  = 7.52%; 95% PI 0.16–1.45), less changes in postoperative humeral head height (MD − 2.40; 95% CI − 2.49 to − 2.31; I 2  = 0.00%; 95% PI − 2.61 to − 2.20) and the neck–shaft angle (MD − 6.30; 95% CI − 7.23 to − 5.36; I 2  = 79.32%; 95% PI − 10.06 to − 2.53), superior functional outcomes (Constant–Murley score: MD 5.07; 95% CI 3.40 to 6.74; I 2  = 0.00%; 95% PI 2.361–7.78; American Shoulder and Elbow Surgeons Score: MD 5.08; 95% CI 3.67 to 6.49; I 2  = 0.00%; 95% PI 1.98–8.18), and better postoperative ROM in terms of forward elevation and external rotation. However, the evidence regarding postoperative abduction was insufficient. Conclusion Meta-analytic pooling of current evidence showed a significant association between the application of FSAs and favourable clinical outcomes in terms of postoperative complications, radiographical findings, functional recovery, and postoperative elevation and external rotation.https://doi.org/10.1186/s13018-022-03211-4Fibular strut augmentationProximal humeral fractureOpen reduction and internal fixationLocking plateReviewMeta-analysis
spellingShingle Wei Nie
Zhaojun Wang
Fei Gu
Shizhuang Xu
Yang Yue
Anze Shao
Kefu Sun
Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysis
Journal of Orthopaedic Surgery and Research
Fibular strut augmentation
Proximal humeral fracture
Open reduction and internal fixation
Locking plate
Review
Meta-analysis
title Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysis
title_full Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysis
title_fullStr Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysis
title_full_unstemmed Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysis
title_short Effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures: a systematic review and meta-analysis
title_sort effects of fibular strut augmentation for the open reduction and internal fixation of proximal humeral fractures a systematic review and meta analysis
topic Fibular strut augmentation
Proximal humeral fracture
Open reduction and internal fixation
Locking plate
Review
Meta-analysis
url https://doi.org/10.1186/s13018-022-03211-4
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